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An introduction to medicinal chemistry

Author: Graham L Patrick
Publisher: Oxford : Oxford University Press, [2013]
Edition/Format:   Book : English : Fifth editionView all editions and formats
Database:WorldCat
Summary:
This volume provides an introduction to medicinal chemistry. It covers basic principles and background, and describes the general tactics and strategies involved in developing an effective drug.
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Document Type: Book
All Authors / Contributors: Graham L Patrick
ISBN: 9780199697397 0199697396
OCLC Number: 810946957
Description: xxiii, 789 pages : illustrations (some color) ; 25 cm.
Contents: Drugs and drug targets - an overview --
Drug targets : structure and function --
Protein structure and function --
Enzymes: structure and function --
Receptors: structure and function --
Receptors and signal transduction --
Nucleic acids: structure and function --
Pharmacodynamics and pharmacokinetics --
Enzymes as drug targets --
Receptors as drug targets --
Nucleic acids as drug targets --
Miscellaneous drug targets --
Pharmacokinetics and related topics --
Statins --
Drug discovery, design, and development --
Drug discovery: finding a lead --
Drug design: optimizing target interactions --
Drug design: optimizing access to the target --
Getting the drug to market --
The design of ACE inhibitors --
Artemisinin and related antimalarial drugs --
The design of oxamniquine --
Tools of the trade --
Combinatorial synthesis --
Computers in medicinal chemistry --
Quantitative structure-activity relationships (QSAR) --
De novo design of a thymidylate synthase inhibitor --
Selected topics in medicinal chemistry --
Antibacterial agents --
Antiviral agents --
Anticancer agents --
Cholinergics, anticholinergics, and anticholinesterases --
Drugs acting on the adrenergic nervous system --
Opioid analgesics --
Antiulcer agents --
Steroidal anti-inflammatory agents --
Design of a novel antidepressant.
Responsibility: Graham L. Patrick.
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Abstract:

An Introduction to Medicinal Chemistry is the leading text for university courses on this subject. Renowned for being a textbook loved equally by both students and lecturers, it presents complete  Read more...

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There is no comparable book... the holy grail for a pharmaceutical science-based course. Doody's Notes, May 2013

 
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