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Ion channels : molecules in action

Author: David J Aidley; Peter R Stanfield
Publisher: Cambridge ; New York : Cambridge University Press, ©1996.
Edition/Format:   Print book : EnglishView all editions and formats
Summary:
Ion channels are crucial components of living cells. They are situated in the membranes of the cell and allow particular ions to pass from one side of the membrane to the other. In recent years the patch clamp technique has allowed the activity of individual channels to be measured, and recombinant DNA technology has revealed fascinating detail on channel structure. Together, these technical advances have produced a
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Material Type: Internet resource
Document Type: Book, Internet Resource
All Authors / Contributors: David J Aidley; Peter R Stanfield
ISBN: 0521495318 9780521495318 0521498821 9780521498821
OCLC Number: 35802714
Description: xii, 307 pages : illustrations ; 26 cm
Contents: 1. Introduction. The discovery of ion channels. Different types of channel --
2. Ions on the move. Electricity. Chemical bonds. Ions in crystals. Ions in solution. Ions moving through membrane channels --
3. Investigating channel activity. Intracellular microelectrodes. The voltage clamp technique. Fluctuation analysis. Artificial phospholipid bilayers. The patch clamp technique. Analysis of single channel current records --
4. Molecular Structures. Determining channel protein sequences. The nicotinic acetylcholine receptor channel. Other neurotransmitter-gated channels. Voltage-gated channels and their relatives.
Responsibility: David J. Aidley, Peter R. Stanfield.
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Abstract:

Located in cell membranes, ion channels determine the passage of ions across them. Ion Channels examines the molecular structure of channels, which helps explain their permeability and selectivity,  Read more...

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'This well-written and well-illustrated book summarises the background and the recent advances. It is aimed at an undergraduate audience but could be understood by any non-specialist with an interest Read more...

 
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