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Ions in the brain : normal function, seizures, and stroke

Author: George G Somjen
Publisher: Oxford ; New York : Oxford University Press, 2004.
Edition/Format:   Print book : EnglishView all editions and formats
Summary:
This book deals with the regulation of ions in brain extra- and intracellular fluids. After an introduction to the electrophysiology of epilepsy, and a description of experimental seizure "models," the second part discusses the roles of the faulty regulation of ions and of the diseases of ion channels in generating epileptic seizures. The mechanisms of action of various anticonvulsant drugs are also considered. The  Read more...
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Additional Physical Format: Online version:
Somjen, George G.
Ions in the brain.
Oxford ; New York : Oxford University Press, 2004
(OCoLC)607140766
Material Type: Internet resource
Document Type: Book, Internet Resource
All Authors / Contributors: George G Somjen
ISBN: 0195151712 9780195151718
OCLC Number: 52341982
Description: xxix, 470 pages : illustrations ; 25 cm
Contents: The blood-brain barrier --
The regulation of brain ions --
Osmotic stress and the brain --
The influence of ion concentrations on neuron functions --
A primer of epileptiform seizures --
Experimental seizures --
Electrophysiology of seizures --
Ions and seizures --
Solving seizure mechanisms by simulations --
Seizures, channels, genes --
Mechanisms of action of antiepileptic drugs --
Introduction to speading depression: extracellular electric signs --
Ion fluxes during spreading depression --
Membrane potential and input resistance during spreading depression --
The mechanism of spreading depression --
Solving the puzzle of spreading depression by computer simulation --
Hypoxia, asphyxia, and ischemia --
Mechanism of early, reversible hypoxic synaptic failure --
Irreversible hypoxic (ischemic) neuron injury.
Responsibility: George G. Somjen.
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Abstract:

This volume deals with the regulation of ions in brain, and the effects of changing ion levels on the excitability of neurons and on synaptic transmission. The roles of ions in generating epileptic  Read more...

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. . . it has a pleasing consistency of style . . . this is an excellent book which is a must read for all interested in the fields covered. While not claiming to tell us how the brain works, Somjen Read more...

 
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