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|Additional Physical Format:||Print version:
Journey through genetics. Part II.
San Rafael, California : Morgan & Claypool Publishers Life Sciences, ©2014
ix, 84 pages
|Material Type:||Document, Internet resource|
|Document Type:||Internet Resource, Computer File|
|All Authors / Contributors:||
|Description:||1 online resource (83 pages) : illustrations.|
|Contents:||9781615046621_ebook_cover.pdf; PDF_blank.pdf; C00114ED1V02Y201407GBD006.pdf; A Journey Through Genetics [Part II] ; Colloquium Digital Library of Life Sciences; Colloquium Series on Genetic Basis of Human Disease; Abstract; Key Words; Contents; History of Genetics Timeline (Part 2); Chapter 1: The Age of the Operon: The Regulation of Gene Expression in E. coli; 1.1 The Operon Model: The Lactose Operon of E. coli ; 1.2 Structural Elements of the Lac Operon ; 1.2.1 Structural Genes (Lac Z, Lac Y, Lac A) ; 1.2.2 The Operator Gene (Lac O) ; 1.2.3 The Regulator Gene (Lac I). 1.3 Functional Regulation of the Lactose Operon 1.3.1 The Role of Induction and Repression in the Lac Operon ; 1.3.2 Attachment of the RNA Polymerase ; 1.3.3 Transcription of the Structural Genes ; 1.4 A Short Educational Skit Based on the Lactose Operon: I Need Energy: A Tale of Two Sugars ; 1.5 What would happen if both glucose and lactose were present in the medium? ; Useful Links: ; Chapter 2: Genetic Diversity: Cheetah Chatter; 2.1 The Journey Into Africa ; 2.2 Proteins in the cheetah's blood were separated and analyzed using a technique called Protein Gel. 2.3 A second line of evidence from MHC proteins and skin grafts 2.4 Genetic Diversity ; 2.5 Cheetahs and the Bottleneck Effect ; Useful Links: ; Chapter 3: Gene Cloning and Recombinant DNA Technology; 3.1 Gene manipulation/Genetic engineering can be divided into two steps (Figure 3.1): ; 3.2 Characteristic Features of Cloning Vectors ; 3.3 Applications of Genetic Engineering ; Chapter 4: Applications of Genetic Engineering-Resurrecting the 1918 Influenza Virus; 4.1 The Journey ; 4.1.1 Resurrection ; 4.1.2 The One that Got Away ; 4.1.3 Reverse Engineering a Killer Virus ; Useful Links. Chapter 5: The Human Journey5.1 Spencer Wells and the Genographic Project ; 5.1.1 In the beginning ... ; 5.2 How do we know that this amazing journey started in Africa? ; 5.2.1 Mapping Markers on Y Chromosomes ; 5.2.2 STR Markers ; 5.2.3 Mitochondrial Eve and Female Mitochondrial Markers ; 5.2.4 Mapping Single Nucleotide Polymorphisms on Mitochondrial DNA ; 5.2.5 The Journey of the Y chromosome (Figure 5.5): ; 5.2.6 The Journey Out of Africa (The M168 Marker) ; 5.2.7 The First Route Out of Africa and On to Australia ; 5.2.8 Journeying On to Australia (M130 Marker). 5.2.9 The Second Route Out of Africa to Central Asia 5.2.10 Forty Thousand Years Ago Modern Humans Reach Central Asia ; 5.2.11 Following the M45 (Migrating East) ; 5.2.12 The Longest Journey: 50,000 Years and People Reach South America (The M3 Marker) ; 5.2.13 What Did You Learn from this Journey? ; Useful Links: ; Chapter 6: The Three-Dimensional Folding of the Genome; 6.1 Beads on a String ; 6.1.1 The Nucleosome Concept: The First Level of Folding ; 6.1.2 Nucleosomes Unraveled ; 6.2 Linker Histone and Linker DNA ; 6.3 Higher-Order Folding of Chromatin.|
|Series Title:||Colloquium series on the genetic basis of human disease, 6.|