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Kinase drug discovery

Author: Richard A Ward; Fred Goldberg
Publisher: Cambridge, U.K. : Royal Society of Chemistry, ©2012.
Series: RSC drug discovery series, 19.
Edition/Format:   eBook : Document : EnglishView all editions and formats
Summary:

This is the first book to examine the future opportunities and challenges in the development of drugs which target kinases

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Genre/Form: Electronic books
Additional Physical Format: Print version:
Kinase drug discovery.
Cambridge : Royal Society of Chemistry, ©2012
(OCoLC)774634151
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Richard A Ward; Fred Goldberg
ISBN: 9781849733557 1849733554
OCLC Number: 775569468
Description: 1 online resource (xiii, 318 pages) : illustrations (some color).
Contents: An Introduction to Kinase Inhibition; The Kinome and its Impact on Medicinal Chemistry; Contemporary Approaches to Kinase Lead Generation; The Learning and Evolution of Medicinal Chemistry against Kinase Targets; The Mechanism and Kinetics of Kinase Inhibitors; Kinase mutations and resistance in cancer; Non-Protein Kinases as Therapeutic Targets; The Drug Discovery and Development of Kinase Inhibitors Outside of Oncology; Allosteric Activators of Glucokinase (GK) for the Treatment of Type 2 Diabetes; Drug Discovery and Non-Human Kinomes; The future of kinase drug discovery
Series Title: RSC drug discovery series, 19.
Responsibility: edited by Richard A. Ward and Frederick Goldberg.

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"This concise book links diverse topics well to support the creativity that is now vigorously driving protein kinase inhibitor research." -- Prof. Richard Engh, University of Tromso (Norway) Read more...

 
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