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Lesions and transplantation

Author: P Michael Conn
Publisher: San Diego, Calif. : Academic Press, [1991] ©1991
Series: Methods in neurosciences, v. 7.
Edition/Format:   eBook : Document : EnglishView all editions and formats
Database:WorldCat
Summary:
Methods in Neurosciences, Volume 7: Lesions and Transplantation describes the chemical and nonchemical production of lesions and preparation and development of transplants, implants, and grafts. This book consists of four sections-chemical and nonchemical lesioning; model systems utilizing lesioning; transplants, implants, and grafts; and assessment of lesions and transplants. In these sections, this volume  Read more...
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Genre/Form: Electronic books
Additional Physical Format: Print version:
Lesions and transplantation
(OCoLC)24675837
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: P Michael Conn
ISBN: 9781483259505 1483259501
OCLC Number: 881472647
Description: 1 online resource (xvii, 496 pages) : illustrations.
Contents: Front Cover; Lesions and Transplantation; Copyright Page; Table of Contents; Preface; Methods in Neurosciences; Section I: Chemical and Nonchemical Lesioning; Chapter 1. Lesioning of Rat Nigrostriatal Dopamine Pathway with l-Methyl-4-phenylpyridinium Ion (MPP+); Introduction; Methods; Evaluation of the Lesion; Conclusion; References; Chapter 2. Excitotoxins as Tools for Producing Brain Lesions; Introduction; Excitotoxins: Classification, Comparison, and Mechanisms; Use of Excitotoxins to Make Lesions; Summary; Acknowledgments; References; Chapter 3. Excitotoxin-Lesioned Rat Striatum; Methods AcknowledgmentsReferences; Chapter 4. Use of Acromelic Acid for Production of Rat Spinal Lesions ; Acromelic Acid; Injection of Acromelic Acid into Rats and Mice; Kainoid Neurotoxicity; Electrophysiological and Pharmacological Basis; Behavioral Basis; Histological Basis; References; Chapter 5. Use of Ibotenic Acid to Selectively Lesion Brain Structures ; Methods and Procedures; Additional Considerations; Is There Damage to Fibers of Passage following IBO Injections?; Conclusions; Acknowledgments; References; Chapter 6. Monosodium Glutamate (MSG) Lesions; Introduction; Mechanism of Action Histology of LesionsProcedures; MSG Syndrome; Histochemical Changes; Summary; References; Chapter 7. Comparison of Electrolytic and Radio-Frequency Lesion Methods; Introduction and Historical Background; Different Effects Observed with Electrolytic and Radio-Frequency Lesions; Production of Electrolytic Lesions; Production of Radio-Frequency Lesions; Production and Verification of Lesions That Leave No Metallic Ion Deposits; Summary and Conclusion; References; Chapter 8. Use of Cold to Reversibly Suppress Local Brain Function in Behaving Animals ; Moveable Cryodes Permanently Implanted CryodesAcknowledgment; References; Chapter 9. Chorioretinal Photocoagulation by Different Laser Sources; Introduction; Photocoagulation; Laser Power; Exposure Time; Spot Size; Laser Photocoagulators; Transpupillary Photocoagulation; Transscleral Photocoagulation; Endoocularphotocoagulation; References; Chapter 10. Production of Reversible Local Blockage of Neuronal Function; Introduction; Local Cooling of the CNS; Local Anesthesia; Other Chemicals; Summary; References; Chapter 11. Lesioning the Nucleus Basalis; Introduction; Lesioning Methods; Conclusions; References Section II: Model Systems Utilizing LesioningChapter 12. Unilateral MPTP-Lesioned Monkey as an Animal Model for Parkinson's Disease; Parkinson's Disease; 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine (MPTP); Bilateral versus Unilateral MPTP-Treated Monkeys; MPTP Application; The Unilateral MPTP-Lesioned Monkey; Conclusions; Acknowledgments; References; Chapter 13. MPTP-Induced Parkinsonism in Nonhuman Primates ; Species; MPTP Administration; Clinical Outcome of MPTP Administration; Histological Changes after MPTP Administration; Neurochemical Changes after MPTP Administration
Series Title: Methods in neurosciences, v. 7.
Responsibility: edited by P. Michael Conn.

Abstract:

This volume describes recent techniques used in neuropeptide technology, for example, in the identification and purification of neuropeptides, in neuropeptide synthesis, the identification of  Read more...

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