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LHRH and its analogs : contraceptive and therapeutic applications

Author: Brian H Vickery; J J Nestor; E S E Hafez
Publisher: Lancaster [Lancashire] ; Boston : MTP Press, ©1984-©1987.
Series: Advances in reproductive health care.
Edition/Format:   Print book : Conference publication : EnglishView all editions and formats
Summary:

In order to track this expanding field, I was asked to organize an international symposium on basic and clinical aspects of LHRH analogs as part of the Reproductive Health Care: CDS Symposium held in  Read more...

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Genre/Form: Conference papers and proceedings
Congresses
Congrès
Material Type: Conference publication
Document Type: Book
All Authors / Contributors: Brian H Vickery; J J Nestor; E S E Hafez
ISBN: 0852007329 9780852007327
OCLC Number: 10506144
Notes: Part 2 edited by B.H. Vickery and J.J. Nestor Jr.
Description: 2 volumes : illustrations ; 24 cm.
Contents: Section I. Chemistry and Basic Reproductive Properties.- 1 Development of agonistic LHRH analogs.- 2 LHRH analogs as antiovulatory agents.- 3 LHRH agonists and antagonists containing very hydrophobic amino acids.- 4 Pharmacological regulation of pituitary LHRH receptors.- Section II. Reproductive Physiology and Pharmacology in Laboratory Animals.- 5 Biological assays utilized to characterize LHRH and its analogs.- 6 Male contraceptive potential of nafarelin acetate assessed in the dog.- 7 Male fertility control with an LHRH agonist: primate studies.- 8 LHRH agonists for control of female fertility: primate studies.- 9 LHRH antagonists in rhesus and cynomolgus monkeys.- 10 LHRH antagonists in females.- 11 Biological evaluation of a highly potent LHRH antagonist.- 12 LHRH antagonists for male contraception.- Section III. Extrahypophysial Parameters.- 13 Direct antigonadal actions of LHRH.- 14 Direct gonadal stimulation with LHRH.- 15 Antisteroidal actions of LHRH agonists.- Section IV. Contraception in Women.- 16 LHRH agonists for female contraception.- 17 Postcoital contraception with intranasal buserelin.- 18 Antifertility by discontinuous treatment with buserelin in women.- 19 Risks and benefits of LHRH agonists as antifertility agents.- Section V. Contraception in Men.- 20 Effects of nafarelin acetate in men.- 21 Antifertility effects of an LHRH agonist in men.- Section VI. Human Therapeutic Applications.- 22 LHRH therapy for hypogonadotropic hypogonadal men.- 23 Correction of infertility with LHRH agonists in the male.- 24 LHRH analog therapy of precocious puberty.- 25 LHRH analogs for human mammary carcinoma.- 26 Buserelin therapy for prostatic carcinoma.- 27 Leuprolide therapy for prostatic carcinoma.- Section VII. Diagnostic Applications of Lhrh.- 28 Diagnostic uses of LHRH.- Section VIII. Applications in Animals.- 29 Actions of LHRH and its analogs in lower vertebrates.- 30 LHRH and analogs in relation to livestock.- Section IX. Metabolic Parameters.- 31 Enzymatic degradation of LHRH and analogs.- 32 Metabolism of [d-Trp6]LHRH.- 33 Absorption and metabolism of LHRH and analogs.- Section X. Perspectives.- 34 Prospects for LHRH analogs as contraceptives.- 35 The therapeutic potential of LHRH and LHRH analogs.- 36 Epilog.- J. J. Nestor Jr..
Series Title: Advances in reproductive health care.
Other Titles: L.H.R.H. and its analogs
Responsibility: editors, B.H. Vickery, J.J. Nestor, Jr., and E.S.E. Hafez.

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