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Life-span extension : single-cell organisms to man

Author: Christian Sell; Antonello Lorenzini; Holly M Brown-Borg
Publisher: Totowa, N.J. : Humana ; London : Springer [distributor], 2009.
Series: Aging medicine.
Edition/Format:   eBook : Document : EnglishView all editions and formats
Database:WorldCat
Summary:
Many discoveries are made in underlying mechanisms of aging. This book brings together perspectives from researchers investigating aging process in a variety of species. It aims to address aging process in species ranging from yeast to man. It carries discussions of the naked mole-rat, an exceptionally long-lived rodent, among other subjects.
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Genre/Form: Electronic books
Additional Physical Format: Print version:
Life-span extension.
Totowa, N.J. : Humana ; London : Springer [distributor], 2009
(OCoLC)390940416
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Christian Sell; Antonello Lorenzini; Holly M Brown-Borg
ISBN: 9781603275071 160327507X 9781603275064 1603275061
OCLC Number: 437346550
Description: 1 online resource (xvii, 198 pages) : illustrations (some color).
Contents: Introduction / Christian Sell --
Part I: Yeast. Reprogramming cell survival and longevity: The role of Tor, Sch9, Ras, and Sir2 / Valter D. Longo --
Part II: Caenorhabditis elegans. Common aging mechanisms: energy metabolism and longevity in Caenorhabditis elegans / Marta Artal-Sanz and Nektarios Tavernarakis ; Conserved mechanisms of life-span regulation and extension in Caenorhabditis elegans / Sean P. Curran --
Part III: Drosophila melanogaster. The genetic architecture of longevity / Robert Arking ; Mild stress and life extension in Drosophila melanogaster / Éric Le Bourg --
Part IV: Rodents. Global food restriction / Michelle E. Matzko, Roger J. McCarter, and Edward J. Masoro ; Growth hormone and aging in mice / Holly M. Brown-Borg, Sunita Sharma, Kurt E. Borg, and Sharlene G. Rakoczy --
Part V: Comparative biology of aging. Exploiting natural variation in life span to evaluate mechanisms of aging / Rochelle Buffenstein ; Slow aging: insights from an exceptionally long-lived rodent, the naked mole-rat / Rochelle Buffenstein and Yael H. Edrey ; Life extension in the short-lived fish Nothobranchius furzeri / Alessandro Cellerino --
Part VI: Aging in humans. Aging and longevity in animal models and humans / Miriam Capri, Stefano Salvioli, Elisa Cevenini, Laura Celani, Federica Sevini, Elena Bellavista, Catia Lanzarini, Stella Lukas, Paolo Tieri, Francesco Lescai, Daniela Monti, and Claudio Franceschi.
Series Title: Aging medicine.
Responsibility: edited by Christian Sell, Antonello Lorenzini, Holly M. Brown-Borg.

Abstract:

In recent years, remarkable discoveries have been made concerning the underlying mechanisms of aging. This multidisciplinary book brings together a range of illuminating perspectives from researchers  Read more...

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From the reviews:"This multiauthored book reviews the mechanisms of life-span extension across the animal kingdom, including man. ... The audience here is researchers into the nature of aging and Read more...

 
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