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Lipid lowering agents for stroke prevention : a review of the clinical evidence, safety and guidelines

Author: Canadian Agency for Drugs and Technologies in Health.
Publisher: [Ottawa, Ont.] : Canadian Agency for Drugs and Technologies in Health, 2012
Series: Rapid response report.
Edition/Format:   eBook : Document : English
Summary:
Dyslipidemia, a risk factor for developing cardiovascular disease, is characterized by an abnormal amount of lipids in the blood and can be managed by several lipid lowering agents including fibrates, nicotinic acid, ezetimibe, and statins. 4 The most effective and commonly prescribed lipid lowering agents to date are HMG-CoA reductase inhibitors or statins. Lipid lowering agents have been prescribed in decreasing  Read more...
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Genre/Form: Electronic books
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Canadian Agency for Drugs and Technologies in Health.
OCLC Number: 793583405
Notes: "8 March 2012."
Description: 1 online resource (26 pages) : tables, digital file.
Series Title: Rapid response report.
Responsibility: [prepared by Canadian Agency for Drugs and Technologies in Health].
More information:

Abstract:

Dyslipidemia, a risk factor for developing cardiovascular disease, is characterized by an abnormal amount of lipids in the blood and can be managed by several lipid lowering agents including fibrates, nicotinic acid, ezetimibe, and statins. 4 The most effective and commonly prescribed lipid lowering agents to date are HMG-CoA reductase inhibitors or statins. Lipid lowering agents have been prescribed in decreasing frequency in older adults due to a perceived lack of evidence for benefit and safety concerns. Since the CVD burden is so great in this population, there is substantial potential for lipid lowering treatments to provide benefit in this population. This review evaluates the efficacy and safety of lipid lowering agents for stroke prevention in elderly patients to provide an evidence base to formulate guidelines.

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