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MACPF/CDC proteins : agents of defence, attack and invasion

Author: Gregor Anderluh; Robert Gilbert
Publisher: Dordrecht : Springer, [2014] ©2014
Series: Sub-cellular biochemistry, v. 80.
Edition/Format:   Print book : EnglishView all editions and formats
Summary:

This book focusses on evolutionary, structural and functional aspects of pore-forming proteins, bringing together prominent researchers in the fields of structural biology and cellular and  Read more...

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Additional Physical Format: (GyWOH)har145010554
Online version:
MACPF/CDC proteins-- agents of defence, attack and invasion.
Dordrecht : Springer, 2014
(OCoLC)879679217
Document Type: Book
All Authors / Contributors: Gregor Anderluh; Robert Gilbert
ISBN: 9789401788809 9401788804
OCLC Number: 880841338
Description: xi, 329 pages : illustrations (some color) ; 24 cm.
Contents: Introduction: brief historical overview --
Distribution of MACPF/CDC proteins --
Evolution of the complement system --
Structural features of cholesterol dependent cytolysins and comparison to other MACPF-domain containing proteins --
Perfringolysin O structure and mechanism of pore formation as a paradigm for cholesterol-dependent cytolysins --
Structural biology of the membrane attack complex --
Membrane interactions and cellular effects of MACPF/CDC proteins --
The biology of pneumolysin --
Multifaceted activity of listeriolysin O, the cholesterol -dependent cytolysin of Listeria monocytogenes --
Perforin: a key pore-forming protein for immune control of viruses and cancer --
Perforin and human diseases --
The role of MACPF proteins in the biology of malaria and other apicomplexan parasites --
Chlamydial MACPF protien CT153 --
Fungal MACPF-like proteins and aegerolysins: bi-component pore-forming proteins? --
Fluorescence imaging of MACPF/CDC proteins: new techniques and their application.
Series Title: Sub-cellular biochemistry, v. 80.
Responsibility: Gregor Anderluh, Robert Gilbert, editors.

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