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Malondialdehyde (MDA) : structure, biochemistry and role in disease

Author: Jackson Campbell
Publisher: New York : Nova Science Publishers, Inc., [2015] ©2015
Series: Biochemistry research trends series.
Edition/Format:   eBook : Document : EnglishView all editions and formats
Summary:
Malondialdehyde (MDA) is one of the better-known secondary products of lipid peroxidation, and it can be used in biomaterials as an indicator of cell membrane injury. The first chapter offers an overview of the implications of MDA on oxidative stress, and therefore in neurogenerative diseases, as well as collects information of several natural products that exert beneficial properties on oxidative stress-related  Read more...
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Genre/Form: Electronic books
Additional Physical Format: Print version:
Campbell, Jackson.
Malondialdehyde (MDA) : Structure, Biochemistry and Role in Disease.
Hauppauge : Nova Science Publishers, Inc., ©2015
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Jackson Campbell
ISBN: 9781634828079 1634828070
OCLC Number: 913742560
Description: 1 online resource.
Contents: MALONDIALDEHYDE (MDA): STRUCTURE, BIOCHEMISTRY AND ROLE IN DISEASE; MALONDIALDEHYDE (MDA): STRUCTURE, BIOCHEMISTRY AND ROLE IN DISEASE; Library of Congress Cataloging-in-Publication Data; Contents; Preface; Chapter 1: Involvement of Malondialdehyde in Oxidative Stress and Neurodegenerative Diseases; Abstract; 1. Oxidative Stress, Lipid Peroxidation and Malonyldialdehyde (MDA); 1.1. Oxidative Stress; 1.2. Lipid Peroxidation; Autoxidation: Non-enzymatic Lipid Peroxidation; Photo-oxidation; Enzymatic Lipid Oxidation; 1.3. Malonyldialdehyde (MDA). 2. Malondialdehyde (MDA) and Its Role in Biology of Neurodegenerative Diseases3. Methods for MDA Detection; 4. Natural Products with Beneficial Effects on Lipid Peroxidation in Oxidative Stress-related Neurodegenerative Diseases; References; Chapter 2: Impact of Malondialdehyde on Cognitive Dysfunction in Obesity; Abstract; 1. Introduction; 2. Obesity, Circulating Malondialdehyde Levels and Insulin Resistance: Possible Mechanisms and Consequences; 3. Peripheral and Brain Insulin Resistance, and Cognitive Decline. 4. The Association of Malondialdehyde Levels and Cognitive Decline Under Obese-insulin Resistant ConditionsConclusion; Acknowledgements; References; Chapter 3: Glutathione and Lipoic Acid Benefit Effects on Liver, Kidney, Brain and Pancreatic Tissue from Cd-, Pb- and Cu- Provoked Lipid Peroxidation Monitoring via MDA Content among Wistar Rats; Abstract; Introduction; Lipid Peroxidation; Malondialdehyde (MDA); Antioxidants in Biological Systems; Glutathione (GSH); Lipoic acid (LA); Metal Toxicity; Lead; Cadmium; Copper; MDA under the Conditions of Chronic Lead Intoxication. MDA under the Conditions of Acute Cadmium IntoxicationMDA under the Conditions of; Chronic Copper Intoxication; Protective Role of GSH and LA; Conclusion; Acknowledgments; References; Index.
Series Title: Biochemistry research trends series.
Responsibility: Jackson Campbell, editor.

Abstract:

Malondialdehyde (MDA) is one of the better-known secondary products of lipid peroxidation, and it can be used in biomaterials as an indicator of cell membrane injury. The first chapter offers an overview of the implications of MDA on oxidative stress, and therefore in neurogenerative diseases, as well as collects information of several natural products that exert beneficial properties on oxidative stress-related diseases by modulating MDA levels. The second chapter in this book focuses on the role of malondialdehyde in the development of insulin resistance in obesity. The chapter also comprehe.

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