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The many faces of osteoarthritis

Author: Vincent C Hascall; Klaus E Kuettner
Publisher: Basel ; Boston : Birkhäuser Verlag, ©2002.
Edition/Format:   Print book : Conference publication : EnglishView all editions and formats
Summary:

Osteoarthritis is the most common joint pathology which primarily affects the older population. The disease is characterized by unique pathological changes in some synovial joints, predominantly  Read more...

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Genre/Form: Congresses
Aufsatzsammlung
Conference papers and proceedings
Material Type: Conference publication, Internet resource
Document Type: Book, Internet Resource
All Authors / Contributors: Vincent C Hascall; Klaus E Kuettner
ISBN: 9783764365813 3764365811
OCLC Number: 50155251
Description: xl, 495 pages : illustrations, portraits
Contents: Type IIA procollagen NH2-propeptide functions as an antagonist of bone morphogenetic proteins.- Genetics and osteoarthritis.- Metabolic differences between knee and ankle.- Prevention of lower limb osteoarthritis: Data from The Johns Hopkins Precursors Study.- The inheritance of hip osteoarthritis in Iceland.- Dynamics of matrix loss in the spontaneous osteoarthritic mouse stran STR-1N.- Identification and characterization of human cell populations capable of forming stable hyaline cartilage in vivo.- Osteogenic protein-1 promotes proteoglycan synthesis and inhibits cartilage degeneration mediated by fibronectin-fragments.- Osteogenic protein-1 and its receptors in human articular cartilage.- Behringer The transcription factors L-SoxS and Sox6 are essential for cartilage formation.- Amelogenin peptides have unique milieu-dependent roles in morphogenic path determination.- Electron microscope studies of collagen fibril formation in cornea, skin and tendon: Implications for collagen fibril assembly and structure in other tissues.- Hyaluronics and aggrecanics.- Lectin domains in hyaluronan-binding proteoglycans.- The matrilins: A novel family of extracellular adaptor proteins.- Superficial zone protein (SZP) is an abundant glycoprotein in humansynovial fluid with lubricating properties.- Establishment of in vitro cell culture models for the investigation of the pathogenesis of cartilage diseases.- Role of hyaluronan in regulating joint fluid flow.- Elastoviscous hyaluronan in the synovium in health and disease.- The covalent complex formation of hyaluronan with heavy chains ofinter-a-trypsin inhibitor family is important for its functions.- Spicer In vivo investigation of hyaluronan and hyaluronan synthase-2 function during cartilage and joint development.- CD44 and cartilage matrix stabilization.- Metalloproteinases and osteoarthritis.- Age-dependent changes in some physico-chemical properties of human articular cartilage.- The role of the bone/cartilage interface in osteoarthritis.- Dualistic role of TG Fss in osteoarthritis cartilage destruction and osteophyte formation.- Collagen cross-links as markers of bone and cartilage degradation.- Markers of joint tissue turnover in osteoarthritis.- Gene expression profiling by the cDNA array technology: Molecular portraying of chondrocytes.- Clinical evaluation of markers for osteoarthritis.- Joint degradation in rapidly destructive and hypertrophic osteoarthritis of the hip.- Differential gene trap: A new strategy for identifying genes regulated during cartilage differentiation.- Imaging cartilage changes in osteoarthritis.- Diffraction enhanced x-ray imaging of articular cartilage.- Bone changes in osteoarthritis.- Radiographic joint space width (JSW): A marker of disease progression in osteoarthritis of the hip.- Small proteoglycans in knee and ankle cartilage.- Fixed charge density and cartilage biomechanics.- Influence of tissue shear deformation on chondrocyte biosynthesis and matrix nano-electromechanics.- The biomechanical faces of articular cartilage in growth, aging, and osteoarthritis.- Cartilage tissue engineering using a new self-assembling peptide gel scaffold..- Differential effects of IL-1 ss on human knee and ankle chondrocytes.- Dynamic function and imaging in the analysis of osteoarthritis at the knee.- Linking the biology of osteoarthritis to locomotion mechanics.- Movement patterns of individuals with good potential to dynamically stabilize their knees after acute ACL rupture.- Neuromuscular control of the ACL deficient knee: Implications for the development of osteoarthritis.
Responsibility: Vincent C. Hascall, Klaus E. Kuettner, editors.

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