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Mathematical and statistical methods for genetic analysis

Author: Kenneth Lange
Publisher: New York : Springer, ©2002.
Series: Statistics for biology and health.
Edition/Format:   Print book : English : 2nd edView all editions and formats
Summary:

Written to equip students in the mathematical siences to understand and model the epidemiological and experimental data encountered in genetics research. This second edition expands the original  Read more...

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Genre/Form: Statistics
Aufsatzsammlung
Material Type: Internet resource
Document Type: Book, Internet Resource
All Authors / Contributors: Kenneth Lange
ISBN: 0387953892 9780387953892
OCLC Number: 48170937
Description: xvii, 361 pages : illustrations ; 24 cm.
Contents: Basic principles of population genetics --
Counting methods and the EM algorithm --
Newton's method and scoring --
Hypothesis testing and categorical data --
Genetic identity coefficients --
Applications of identity coefficients --
Computation of Mendelian likelihoods --
The polygenic mode; --
Descent graph methods --
Molecular phylogeny --
Radiation hybrid mapping --
Models of recombination --
Sequence analysis --
Poisson approximation --
Diffusion processes --
Appendix A: Molecular genetics in brief --
Appendix B: The normal distribution.
Series Title: Statistics for biology and health.
Responsibility: Kenneth Lange.
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From the reviews of the second edition:"This book is an excellent resource for statisticians and applied mathematicians seeking an overview of models and formalisms in use in a wide collection of Read more...

 
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