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Mechanism-based therapies for heart failure and cardiac arrhythmias

Author: Andrew R Marks
Publisher: London : Henry Stewart Talks, 2007.
Series: Henry Stewart talks., Biomedical & life sciences collection., Calcium signaling : regulation, mechanisms, effectors, role in disease and recent advances.
Edition/Format:   eVideo : Clipart/images/graphics : EnglishView all editions and formats
Database:WorldCat
Summary:
Audio-visual presentation : Introduction to excitation-contraction coupling ; History of the field of EC coupling ; Introduction to the ryanodine receptor/calcium release channel (RyR2) ; Mechanisms that regulate the RyR2 channel during stress ; Defective regulation of RyR2 in heart failure ; Evidence that diastolic sarcoplasmic reticulum (SR) calcium leak causes heart failure and arrhythmias in vivo ; Novel  Read more...
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Details

Material Type: Clipart/images/graphics, Internet resource, Videorecording
Document Type: Internet Resource, Computer File, Visual material
All Authors / Contributors: Andrew R Marks
OCLC Number: 310380990
Notes: Title from title frames.
Animated audio-visual presentation with synchronized narration.
Description: 1 streaming video file (48 min.) : digital, mono, SWF file, sound, color.
Details: Mode of access: World Wide Web.; System requirements: Operating System: PC Windows 2000+, Mac OSX+ 3.2. Browser Compatibility: IE6+, Firefox 2+, Opera 9+, Safari 2+ 3.3. Browser settings: enable JavaScript, enable popups from the Henry Stewart Talks site. 3.4. Required Browser Plugins & Viewers: Adobe (Macromedia) Flash Player 7+, Adobe Acrobat Reader 6.0+.
Contents: Introduction to excitation-contraction coupling --
History of the field of EC coupling --
Introduction to the ryanodine receptor/calcium release channel (RyR2) --
Mechanisms that regulate the RyR2 channel during stress --
Defective regulation of RyR2 in heart failure --
Evidence that diastolic sarcoplasmic reticulum (SR) calcium leak causes heart failure and arrhythmias in vivo --
Novel therapeutic approaches to treating heart failure and preventing sudden cardiac death by fixing the leak in RyR2 channels.
Series Title: Henry Stewart talks., Biomedical & life sciences collection., Calcium signaling : regulation, mechanisms, effectors, role in disease and recent advances.
Responsibility: Andrew R. Marks.
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Abstract:

Audio-visual presentation : Introduction to excitation-contraction coupling ; History of the field of EC coupling ; Introduction to the ryanodine receptor/calcium release channel (RyR2) ; Mechanisms that regulate the RyR2 channel during stress ; Defective regulation of RyR2 in heart failure ; Evidence that diastolic sarcoplasmic reticulum (SR) calcium leak causes heart failure and arrhythmias in vivo ; Novel therapeutic approaches to treating heart failure and preventing sudden cardiac death by fixing the leak in RyR2 channels.

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