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Mechanism of enzyme action

Author: Stephen Allen Kuby
Publisher: Boca Raton : CRC Press, ©1991.
Series: Study of enzymes, v. 2.
Edition/Format:   Print book : EnglishView all editions and formats

Focuses on several aspects of enzyme catalytic behavior, their steady-state and transient-state kinetics, and the thermodynamic properties of substrate binding. This book presents examples of  Read more...


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Material Type: Internet resource
Document Type: Book, Internet Resource
All Authors / Contributors: Stephen Allen Kuby
ISBN: 0849369886 9780849369889
OCLC Number: 21875151
Description: 608 pages : illustrations ; 27 cm.
Contents: Some Theoretical Aspects of Enzyme Mechanisms: Mechanical Force, Hydration, and Conformational Fluctuations in Enzymic Catalysis (R. Lumry). Complexation and Catalysis in Biology (R.J.P. Williams). Mechanistic Role of Biotin in Enzymatic Carboxylation Reactions (A.S. Mildvan, D.C. Fry, and E.H. Serpersu). Thiamin-Dependent Reactions (Mechanisms) (C.J. Gubler). Allostery and Non-Michaelis-Menten Behavior: Glycogen Phosphorylase and Glycogen Synthetase (N.B. Madsen). Proteases-Structures and Mechanisms: Calcium-Activated Neutral Protease (K. Imahori, K. Suzuki, and S. Kawashima). Dehydrogenases-Structure and Catalytic Mechanisms: Glutamate Dehydrogenase (Bovine Liver) (R.F. Colman). Dihydrofolate Reductase (J.F. Morrison). 2-Oxoacid Dehydrogenases (M. Hamada and H. Takenaka). Flavoprotein Catalysis: Old Yellow Enzyme (L.M. Schopfer and V. Massey). D-Amino Acid Oxidase (K. Yagi). Cytochrome c, Quinone, and Cytochrome P-450 Reductases (M.S. Johnson and S.A. Kuby). Activated Oxygen Reactions: Dioxygenases and Monooxygenases (S. Yamamoto and Y. Ishimura). ATP-ases, Nucleotide Binding Carriers, and Nucleotidyl Transferases: Ca2+, Mg2+-ATPase (Microsomal) (H. Takenaka, M. Sumida, and M. Hamada). Mechanistic and Energetic Aspects of Carrier Catalysis-Exemplified with Mitochondrial Translocators (M. Klingenberg). Terminal Deoxynucleotidyl Transferase (M.J. Modak and V.N. Pandey). Phosphotransferases-Structure and Mechanisms: Adenylate Kinase (M. Hamada, H. Takenaka, M. Sumida, and S.A. Kuby). Phosphofructokinase and Fructose 6-Phosphate, 2-Kinase: Fructose 2,6-Bisphosphatase (K. Uyeda). Emden-Meyerhof Reactions-Mechanism of Action: Triose- and Hexose-Phosphate Isomerases (K.U. Yuksel and R.W. Gracy). Mechanistic Studies of Muscle Aldolase (D.J. Hupe). Metalloenzymes: Mechanism and Structure of Superoxide Dismutases (J.A. Tainer, V.A. Roberts, C.L. Fisher, R.A. Hallewell, and E.D. Getzoff). Hydrolases-Mechanisms: Phospholipases (G. Arthur and P.C. Choy). Esterases (Including Choline Esterases) (H. Okuda). Lipases (H. Okuda). Index.
Series Title: Study of enzymes, v. 2.
Responsibility: editor, Stephen A. Kuby.
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