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Medication development for the treatment of cocaine dependence : issues in clinical efficacy trials

Author: Betty Tai; C Nora Chiang; Peter Bridge, M.D.; National Institute on Drug Abuse. Office of Science Policy and Communications.
Publisher: Rockville, MD : United States Department of Health and Human Services, National Institutes of Health, National Institute on Drug Abuse, Office of Science Policy and Communications ; [Washington, D.C.] : [Superintendent of Documents, United States Government Publishing Office, distributor], 1997.
Series: NIDA research monograph, 175.; NIH publication, no. 98-4125.
Edition/Format:   Print book : Conference publication : National government publication : EnglishView all editions and formats
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Genre/Form: Congresses
Conference papers and proceedings
Additional Physical Format: Online version:
Medication development for the treatment of cocaine dependence.
Rockville, MD : U.S. Dept. of Health and Human Services, National Institutes of Health, National Institute on Drug Abuse, Office of Science Policy and Communications ; [Washington, D.C. : Supt. of Docs., U.S.G.P.O., distributor], 1997
(OCoLC)623259106
Material Type: Conference publication, Government publication, National government publication, Internet resource
Document Type: Book, Internet Resource
All Authors / Contributors: Betty Tai; C Nora Chiang; Peter Bridge, M.D.; National Institute on Drug Abuse. Office of Science Policy and Communications.
OCLC Number: 38160933
Notes: "Based on the papers from a technical review ... held on October 20-21, 1994"--Page ii.
Shipping list no.: 98-0092-P.
Description: iv, 329 pages : illustrations ; 24 cm.
Contents: Goals and rationale for pharmacotherapeutic approach in treating cocaine dependence: insights from basic and clinical research --
Overview of potential treatment medications for cocaine dependence --
Methodologic recommendations for cocaine abuse clinical trials: a clinician-researcher's perspective --
Management of clinical trials with new medications for cocaine dependence and abuse --
Outcome measurement considerations: pharmacological treatments for substance abuse --
Variability in treatment-seeking cocaine abusers: implications for clinical pharmacotherapy trials --
Baseline assessment, study entry, and stabilization: double-blind clinical trials in drug dependence --
Addiction severity index in clinical efficacy trials of medications for cocaine dependence --
Cognitive-neuromotor assessment of substance abuse: focus on issues related to cocaine abuse treatment --
Treatment effectiveness score as an outcome measure in clinical trials --
Pharmacokinetics of cocaine: considerations when assessing cocaine use by urinalysis --
Quantitative urine levels of cocaine and other substances of abuse --
Use of quantitative urinalysis in monitoring cocaine use --
Is quantitative urinalysis more sensitive? --
Comparison of immunoassays for semiquantitative measurement of benzoylecgonine in urine --
Appendix I: Workshop summary outcome measures and success criteria --
Appendix II: Workshop summary clinical decision tree for cocaine addiction pharmacotherapy.
Series Title: NIDA research monograph, 175.; NIH publication, no. 98-4125.
Responsibility: editors, Betty Tai, Nora Chiang, Peter Bridge.

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