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Medication safety in pregnancy and breastfeeding

Author: Gideon Koren
Publisher: New York : McGraw-Hill, Health Professions Division, ©2007.
Edition/Format:   Print book : EnglishView all editions and formats
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Helps you understand the toxicological effects of prescription and OTC drugs on pregnant women and breastfed children. Drawn from the MotherRisk program at the University of Toronto, this resource is  Read more...

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Genre/Form: Meta-Analysis
Additional Physical Format: Online version:
Koren, Gideon, 1947-
Medication safety in pregnancy and breastfeeding.
New York : McGraw-Hill, Health Professions Division, ©2007
(OCoLC)608583116
Material Type: Internet resource
Document Type: Book, Internet Resource
All Authors / Contributors: Gideon Koren
ISBN: 9780071448284 0071448284
OCLC Number: 77270896
Description: xv, 623 pages : illustrations ; 29 cm
Contents: Contributors --
preface --
pt. 1. Maternal fetal toxicology--
1. Drugs in pregnancy : acknowledging challenges --
finding solutions / Gideon Koren --
2. Gestational changes in drug disposition in the maternal-fetal unit / Christelle Gedeon and Gideon Koren --
3. Developmental risk assessments / Gerald F. Chernoff --
4. Teratogenic drugs and chemicals in humans / Irena Nulman, Yana Izmaylov, Arthur Staroselsky, and Gideon Koren --
5. Epilepsy and pregnancy / Irena Nulman and Gideon Koren --
6. Fetal malformations associated with drugs and chemicals : visualization by sonography/fetal MRI / Irena Nulman, Reuven Sussman, Noah Farber, David Chitayat, and Gideon Koren --
7. Drugs and chemicals most commonly used by pregnant women / Doreen Matsui and David Knoppert --
8. Direct drug toxicity to the fetus / Orna Diav-Citrin and Gideon Koren --
9. Poisoning in pregnancy / Yaron Finkelstein --
10. Maternal disorders leading to increased reproductive risks / Shital Gandhi, Ruth R. Geist, and Alon Shrim --
11. Depression and antidepressant use in pregnancy / Sanjog Kalra and Adrienne Einarson --
12. Neonatal poor adaptation syndrome following in utero exposure to antidepressants / Alaa Ali, Nobuko Taguchi, and Adrienne Einarson. 13. Clinical management of substance use during pregnancy / Lori E. Ross, Gideon Koren, and Meir Steiner --
14. Fetal alcohol spectrum disorder : the central nervous system tragedy / Irena Nulman, Dafna Knittel-Keren, and Gideon Koren --
15. Determination of prenatal exposures / Joey N. Gareri, Julia Klein, and Gideon Koren --
16. Occupational exposures known to be human reproductive poisons / Yedidia Bentur and Gideon Koren --
17. The common occupational exposures encountered by pregnant women / Yedidia Bentur and Gideon Koren --
18. Ionizing and nonionizing radiation in pregnancy / Yedidia Bentur --
19. The use of natural health products in pregnancy and lactation : a clinician's guide / Anna Sivojelezova, Michael Gallo, Enkelejda Bollano, Heather Boon, and Gideon Koren --
20. Folic acid and congenital birth defects : review / Y. Ingrid Goh and Gideon Koren --
21. Teratogen information services around the world / Antonio Addis, Myla E. Moretti, and Lavínia Schüler-Faccini --
22. Motherisk : the Toronto model for counselling in reproductive toxicology / Myla E. Moretti --
23. The way women perceive teratogenic risk : how it can influence decision making during pregnancy regarding drug use or abortion of a wanted pregnancy / Adrienne Einarson. pt. 2. Master ; Motherisk archives of systematic and evaluative reviews --
Section 1 : Methodological aspects --
24. A method for meta-analysis of epidemiological studies / Thomas R. Einarson, J. Steven Leeder, and Gideon Koren --
25. Bias against the null hypothesis in maternal-fetal pharmacology and toxicology / Gideon Koren --
26. Bias against the null hypothesis : the reproductive hazards of cocaine / Gideon Koren, Karen Graham, Heather Shear and Tom Einarson --
27. Reporting bias in retrospective ascertainment of drug-induced embryopathy / Benjamin Bar-Oz, Myla E. Moretti, Guy Mareels, TonyVan Tittleboom, and Gideon Koren --
Section 2 : Maternal morbidities --
28. Fall in mean arterial pressure and fetal growth restriction in pregnancy hypertension : a meta-analysis / P. von Dadelszen, M.P. Orenstein, S.B. Bull, A.G. Logan, G. Koren, and L.A. Magee --
29. Prevalence of depression during pregnancy : systematic review / Heather A. Bennett, Adrienne Einarson, Anna Taddio, Gideon Koren, and Thomas R. Einarson. 30. Perinatal risks of untreated depression during pregnancy / Lori Bonari, Natasha Pinto, Eric Ahn, Adrienne Einarson, Meir Steiner, and Gideon Koren --
31. Malformation rates in children of women with untreated epilepsy : a meta-analysis / Shawn Fried, Eran Kozer, Irena Nulman, Thomas R. Einarson, and Gideon Koren --
32. Pregnancy outcome following non-obstetric surgical intervention / Raanan Cohen-Kerem, Craig Railton, Dana Oren, Michael Lishner, and Gideon Koren --
33. Maternal hyperthermia and the risk for neural tube defects in offspring : systematic review and meta-analysis / Myla E. Moretti, Benjamin Bar-Oz, Shawn Fried, and Gideon Koren --
34. Risk of varicella infection during late pregnancy / Gideon Koren --
Section 3 : Alcohol, caffeine, cocaine and environmental exposure --
35. Association between moderate alcohol consumption during pregnancy and spontaneous abortion, stillbirth and premature birth : a meta-analysis / Niloufar Makarechian, Karen Agro, John Devlin, Eric Trepanier, Gideon Koren, and Thomas R. Einarson --
36. Moderate alcohol consumption during pregnancy and the incidence of fetal malformations : a meta-analysis / Dimitris Polygenis, Sean Wharton, Christine Malmberg, Nagwa Sherman, Debbie Kennedy, Gideon Koren, and Thomas R. Einarson. 37. The role of acetaldehyde in pregnancy outcome after prenatal alcohol exposure / Marjie L. Hard, Thomas R. Einarson, and Gideon Koren --
38. Moderate to heavy caffeine consumption during pregnancy and relationship to spontaneous abortion and abnormal fetal growth : a meta-analysis / Olavo Fernandes, Mona Sabharwal Tom Smiley, Anne Pastuszak --
Gideon Koren, and Thomas Einarson --
39. Fetal effects of cocaine : an updated meta-analysis / Antonio Addis, Myla E. Moretti, Fayyazuddin Ahmed Syed, Thomas R. Einarson, and Gideon Koren --
40. Pregnancy outcome following maternal organic solvent exposure : a meta-analysis of epidemiologic studies / Kristen I. McMartin, Merry Chu, Ernest Kopecky, Thomas R. Einarson, and Gideon Koren --
Section 4 : Use of vitamins, contraceptives and therapeutic drugs --
41. Prenatal multivitamin supplementation and rates of congenital anomalies : a meta-analysis / Y. Ingrid Goh, Enkelejd Bollano, Thomas R. Einarson, and Gideon Koren --
42. Maternal spermicide use and adverse reproductive outcome : a meta-analysis / Thomas R. Einarson, Gideon Koren, David Mattice, and Cim Schechter-Tsafriri --
43. Evidence-based view of safety and effectiveness of pharmacologic therapy for nausea and vomiting of pregnancy (NVP) / Laura A. Magee, Paolo Mazzotta, and Gideon Koren. 44. Fetal genital effects of first-trimester sex hormone exposure : a meta-analysis / Lalitha Raman-Wilns, Alice Lin-in Tseng, Suzanne Wighardt, Thomas R. Einarson, and Gideon Koren --
45. Aspirin consumption during the first trimester of pregnancy and congenital anomalies : a meta-analysis / Eran Kozer, Shekoufeh Nikfar, Adriana Costei, Rada Boskovic, Irena Nulman, and Gideon Koren --
46. Fetal safety of drugs used in the treatment of allergic rhinitis : a critical review / Cameron Gilbert, Paolo Mazzotta, Ronen Loebstein, and Gideon Koren --
47. Use of proton pump inhibitors during pregnancy and rates of major malformations : a meta-analysis / Shekoufeh Nikfar, Mohammad Abdollahi, Myla E. Moretti, Laura A. Magee, and Gideon Koren --
48. The safety of nitrofurantoin during the first trimester of pregnancy : meta-analysis / S. Ben David, T. Einarson, Y. Ben David, I. Nulman, A. Pastuszak, G. Koren --
49. Safety of metronidazole in pregnancy : a meta-analysis / Pascale Burtin, Anna Taddio, Omer Ariburnu, Thomas R. Einarson, and Gideon Koren --
50. Risks and benefits of [beta]-receptor blockers for pregnancy hypertension : overview of the randomized trials / Laura A. Magee, Einat Elran, Shelley B. Bull, Alexander Logan, and Gideon Koren. 51. The safety of oral hypoglycemic agents in the first trimester of pregnancy : a meta-analysis / Sheryl J. Gutzin, Eran Kozer, Laura A. Magee, Denice S. Feig, and Gideon Koren --
52. Pregnancy outcome after first-trimester exposure to metformin : a meta-analysis / Cameron Gilbert, Maria Valois, and Gideon Koren --
53. Pregnancy outcome following first trimester exposure to antihistamines : meta-analysis / Arnold Seto, Tom Einarson, and Gideon Koren --
54. Evaluation of brompheniramine safety in pregnancy / Arnold Seto, Tom Einarson, and Gideon Koren --
55. Birth defects after maternal exposure to corticosteroids : prospective cohort study and meta-analysis of epidemiological studies / Laura Park-Wyllie, Paolo Mazzotta, Anne Pastuszak, Myla E. Moretti, Liuzanne Beique, Laura Hunnisett, Mark H. Friesen, Sheila Jacobson, S. Kasapinovic, Debra Chang, Orna Diav-Citrin, David Chitayat, Irena Nulman, Thomas R. Einarson, and Gideon Koren --
56. Pregnancy outcome after cyclosporine therapy during pregnancy : a meta-analysis / Benjamin Bar Oz, Richard Hackman, Tom Einarson, and Gideon Koren. 57. Systematic review of randomized controlled trials and cohort studies on pregnancy outcome following antiretroviral treatment in pregnancy / Alejandro A. Nava-Ocampo, Haleh Talaie, and Gideon Koren --
58. Neurodevelopment of children exposed in utero to treatment of maternal malignancy / I. Nulman, D. Laslo, S. Fried, E. Uleryk, M. Lishner, and G. Koren --
59. Benzodiazephine use in pregnancy and major malformations or oral cleft : meta-analysis of cohort and case-control studies / Lisa R. Dolovich, Antonio Addis, J.M. Régis Vaillancourt, J.D. Barry Power, Gideon Koren, and Thomas R. Einarson --
60. Safety of fluoxetine during the first trimester of pregnancy : a meta-analytical review of epidemiological studies / Antonio Addis and Gideon Koren --
61. Antidepressant use during pregnancy and the rates of spontaneous abortions : a meta-analysis / Michiel E.H. Hemels. Adrienne Einarson, Gideon Koren, Krista L. Lanctôt, and Thomas R. Einarson --
62. Newer antidepressants in pregnancy and rates of major malformations : a meta-analysis of prospective comparative studies / Thomas R. Einarson and Adrienne Einarson --
63. Major malformations with valproic acid / Gideon Koren, Alejandro A. Nava-Ocampo, Myla E. Moretti, Reuven Sussman, and Irena Nulman --
Index.
Responsibility: Gideon Koren.
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