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Mendelian randomization : methods for using genetic variants in causal estimation

Author: Stephen Burgess; Simon G Thompson
Publisher: Boca Raton, FL : Chapman & Hall/CRC, [2015] ©2015
Series: Chap & Hall/CRC interdisciplinary statics series.
Edition/Format:   eBook : Document : EnglishView all editions and formats
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Genre/Form: Electronic books
Additional Physical Format: Print version:
Burgess, Stephen.
Mendelian randomization
(OCoLC)868379698
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Stephen Burgess; Simon G Thompson
ISBN: 9781466573185 146657318X
OCLC Number: 903245878
Description: 1 online resource.
Contents: Introduction and motivation --
What is Mendelian randomization? --
Assumptions for causal inference --
Methods for instrumental variable analysis --
Examples of Mendelian randomization analysis --
Generalizability of estimates from Mendelian randomization --
Weak instruments and finite-sample bias --
Multiple instruments and power --
Multiple studies and evidence synthesis --
Example : the CRP CHD genetics collaboration --
Future directions.
Series Title: Chap & Hall/CRC interdisciplinary statics series.
Responsibility: Stephen Burgess, Simon G. Thompson.

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"The authors have aimed their book at epidemiologists and medical statisticians but anyone with a basic knowledge of regression will understand most of the contents, because the algebra is kept to a Read more...

 
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