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Mental and Physical Handicaps in connection with Overripeness Ovopathy

Author: P H Jongbloet
Publisher: Dordrecht : Springer Netherlands, 1971.
Edition/Format:   eBook : Document : EnglishView all editions and formats
Summary:
Parents of children born with mental or physical handicaps, tend to face the physician with questions about the origin of the abnormality concerned and the chance of having another child with the same condition. The physician then finds himself in a difficult situation since the causes of the majority of congenital abnormalities remain as yet unknown. In most cases he has to restrict himself to a mere enumeration of  Read more...
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Genre/Form: Electronic books
Additional Physical Format: Print version:
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: P H Jongbloet
ISBN: 9789401029582 940102958X
OCLC Number: 851368145
Description: 1 online resource (152 pages)
Contents: I Overripeness of the egg. Considerations on the aetiology of Goldenhar's syndrome and related congenital dysplasias including chromosomal aberrations --
II The intriguing phenomenon of gametopathy and its disastrous effects on the human progeny --
III An investigation into the occurrence of overripeness ovopathy in the normal population --
IV Month of birth and gametopathy. An investigation into patients with Down's, Klinefelter's and Turner's syndrome --
V Status Bonnevie-Ullrich and Turner's syndrome. Overripeness ovopathy as a unifying concept. I (1971 b) --
VI Status Bonnevie-Ullrich and Turner's syndrome. Overripeness ovopathy as a unifying concept. II. (1971 c) --
VII Diagnostic criteria for overripeness ovopathy.
Responsibility: by P.H. Jongbloet.

Abstract:

Parents of children born with mental or physical handicaps, tend to face the physician with questions about the origin of the abnormality concerned and the chance of having another child with the  Read more...

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   schema:description "Parents of children born with mental or physical handicaps, tend to face the physician with questions about the origin of the abnormality concerned and the chance of having another child with the same condition. The physician then finds himself in a difficult situation since the causes of the majority of congenital abnormalities remain as yet unknown. In most cases he has to restrict himself to a mere enumeration of the signs and symptoms encountered or, at best, to a classification of the syndrome at hand. Efforts are frequently made to connect both the somatic aberrations and the mental deficiency with complications during the later stages of pregnancy, at the time of delivery or in the immediate postnatal period. However, a careful search for such items as abnormal dermatoglyphs, or 'degenerative stigmata', and, in particular, a post-mortem examination of the brain, often indicates that the handicap concerned should be ascribed to factors operating long before the time of birth. Theoretically, the causes of abnormalities present at birth can be listed as of a genetic, germinal or peristatic nature. During the past decades special attention has been paid to both genetic and peristatic factors. The purpose of this thesis is to stress the importance of germinal factors, in particular those which, at least in theory, might lead to disturbances in the ripening process of the human egg. We were put on this track by some data concerning the circumstances under which one of our patients presumably had been conceived."@en ;
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