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Meselson, Stahl, and the replication of DNA : a history of "the most beautiful experiment in biology"

Author: Frederic Lawrence Holmes
Publisher: New Haven, CT : Yale University Press, 2001.
Edition/Format:   eBook : Document : EnglishView all editions and formats
Summary:
In 1957 Matthew Meselson and Frank Stahl produced a landmark experiment confirming that DNA replicates as predicted by the double helix structure Watson and Crick had recently proposed. It also gained immediate renown as a 'most beautiful' experiment whose beauty was tied to its simplicity. This book vividly reconstructs the complex route that led to the Meselson-Stahl experiment and provides an inside view of  Read more...
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Genre/Form: Electronic books
History
Additional Physical Format: Print version:
Holmes, Frederic Lawrence.
Meselson, Stahl, and the replication of DNA.
New Haven, CT : Yale University Press, 2001
(DLC) 2001017701
Named Person: Matthew Meselson; Franklin W Stahl; Matthew Meselson; Franklin W Stahl
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Frederic Lawrence Holmes
ISBN: 9780300129663 0300129661 1281730459 9781281730459
OCLC Number: 228171429
Description: 1 online resource (xii, 503 pages) : illustrations
Contents: ""Contents""; ""Preface""; ""Acknowledgments""; ""Introduction""; ""The Replication Problem""; ""Meselson and Stahl""; ""Twists and Turns""; ""Crossing Fields: Chemical Bonds to Biological Mutants""; ""Dense Solutions""; ""The Big Machine""; ""Working at High Speed""; ""The Unseen Band""; ""One Discovery, Three Stories""; ""An Extremely Beautiful Experiment""; ""Centrifugal Forces""; ""The Subunits of Semiconservative Replication""; ""Images of an Experiment""; ""Afterword""; ""Abbreviations Used in Notes""; ""Notes""; ""Index""
Responsibility: Frederic Lawrence Holmes.
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Abstract:

In 1957 two young scientists produced an experiment confirming that DNA replicates as predicted by the double helix structure Watson and Cricks had proposed. This text reconstructs the complex route  Read more...

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"Holmes has written a remarkable history of one of molecular biology's most significant experiments. His recreation of a seminal time in the development of the field is masterful and detailed, and it Read more...

 
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