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Metabolism of drugs and other xenobiotics

Author: Pavel Anzenbacher; Ulrich M Zanger; Wiley InterScience (Online service)
Publisher: Hoboken, N.J. : Wiley-VCH, 2012.
Edition/Format:   eBook : Document : EnglishView all editions and formats
Summary:
A practice-oriented desktop reference for toxicologists and pharmaceutical researchers, this handbook provides systematic coverage of the metabolic pathways of all major classes of xenobiotics in the human body. The first part briefly reviews the main enzyme systems involved in biotransformation and how they are orchestrated in the body, while parts two to four cover the three main classes of xenobiotics: drugs,  Read more...
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Genre/Form: Electronic books
Additional Physical Format: Print version:
Metabolism of drugs and other xenobiotics.
Hoboken, N.J. : Wiley-VCH, 2012
(OCoLC)787848298
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Pavel Anzenbacher; Ulrich M Zanger; Wiley InterScience (Online service)
ISBN: 9783527630905 3527630902 9783527630912 3527630910
OCLC Number: 798928667
Description: 1 online resource (xxix, 724 pages) : illustrations
Contents: Front Matter --
Biochemistry and Molecular Genetics of Drug Metabolism. Drug-Metabolizing Enzymes₆An Overview / Pavel Anzenbacher, Eva Anzenbacherov̀ --
Cytochromes P450 / F Peter Guengerich --
UDP-Glucuronosyltransferases / Christian P Strassburg, Sandra Kalthoff --
Sulfotransferases / Michael W H Coughtrie --
Glutathione -Transferases / Miroslav Dostalek, Anna-Katarina Stark --
Hydrolytic Enzymes / Bingfang Yan --
Transporting Systems / Anne T Nies, Claudia Resch, Tadashi Namisaki --
Transcriptional Regulation of Human Drug-Metabolizing Cytochrome P450 Enzymes / Zdenek Dvorak --
Importance of Pharmacogenomics / Ulrich M Zanger, Kathrin Klein, Jessica Rieger --
Metabolism of Drugs. Introduction to Drug Metabolism / Ulrich M Zanger --
Central Nervous System Drugs / Pierre Baumann, Christoph Hiemke --
Cardiovascular Drugs / Stephan Riedmaier, Ulrich M Zanger --
Anticancer Drugs / Matthias Schwab, Elke Schaeffeler, Hiltrud Brauch --
Antimicrobial Agents / Chantal Csajka, Oscar Marchetti, Oriol Manuel, Laurent Decosterd, Amalio Telenti --
Drugs against Acute and Chronic Pain / Andrew A Somogyi, Janet K Coller --
Drugs of Abuse (Including Designer Drugs) / Markus R Meyer, Hans H Maurer --
Nicotine Metabolism and its Implications / Andy Z X Zhu, Rachel F Tyndale --
Metabolism of Alcohol and its Consequences / Helmut K Seitz, Sebastian Mueller --
Metabolism of Natural Compounds. Introduction and Overview / Michael Murray --
Flavonoids / Petr Hodek --
St John's Wort (L.) / Miroslav Dostalek, Anna-Katarina Stark --
Food Components and Supplements / Alexandr Parlesak --
Metabolism of Unnatural Xenobiotics. Environmental Pollutants / Marie Stiborova --
Environmental Estrogens / Miroslav Machala, Jan Vondr̀cek --
Biotransformation of Insecticides / Corie A Ellison, Alice L Crane, James R Olson --
Index. pt. 1. Biochemistry and molecular genetics of drug metabolism --
pt. 2. Metabolism of drugs --
pt. 3. Metabolism of natural compounds --
pt. 4. Metabolism of unnatural xenobiotics.
Responsibility: edited by Pavel Anzenbacher and Ulrich M. Zanger.

Abstract:

A practice-oriented desktop reference for medical professionals, toxicologists and pharmaceutical researchers, this handbook provides systematic coverage of the metabolic pathways of all major  Read more...

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Overall therefore, a book which can be read in its own right for the first half and then a valuable source of reference for the second half. A useful tome to have on the bookshelf for anyone in the Read more...

 
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