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Metal ions in neurological systems

Author: W Linert; Henryk Kozłowski, (Professor)
Publisher: New York : Springer, ©2012.
Edition/Format:   eBook : Document : EnglishView all editions and formats
Database:WorldCat
Summary:
Metal ions in the brain are a necessity as well as a poison. The presence of metal ions in the active sites of biological catalysts or metalloproteins and in the biological functioning of nucleic acids is very well documented and they are required for brain activity. On the other hand, metals are very effective in generating oxidative stress. This effect does not only play a role in immunology but also is the root  Read more...
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Genre/Form: Electronic books
Additional Physical Format: Print version:
Metal ions in neurological systems.
New York : Springer, 2012
(DLC) 2012948964
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: W Linert; Henryk Kozłowski, (Professor)
ISBN: 9783709110010 3709110017
OCLC Number: 820845543
Description: 1 online resource.
Contents: 1. R.R. Crichton, D.T. Dexter, R.J. Ward: Brain iron metabolism and its perturbation in neurological diseases --
2. E. Milward et al.: Brain changes in iron loading disorders --
3. I. Paris, J. Segura-Aguilar: The role of metal ions in dopaminergic neuron degeneration in Parkinsonism and Parkinson{u2019}s disease --
4. E. Siakkou, G.N.L. Jameson: Iron, cysteine and neurodegeneration during Parkinson{u2019}s disease --
5. G. Crisponi et al.: Copper uptake and trafficking in the brain --
6. Y. Nishida: Prion diseases and manganism --
7. A. Granzotto, P. Zatta: Metal ions and beta-amyloid: conformational modifications and biological aspects --
8. A. Granzotto et al.: Beta-amyloid toxicity increases with hydrophobicity in the presence of metal ions --
9. Ch. Exley, E.R. House: Aluminium in the human brain --
10. V.M. Nurchi, G. Crisponi, V. Bertolasi, G. Faa, M. Remelli: Aluminium dependent human diseases and chelating properties of aluminium chelatots for bio-medical applications.-11. M. Suwalsky P.L. Henrnandez, C.P. Sotomayor: Aluminum increases toxic effects of amyloid beta-peptides on human erythrocyte membrane and molecular models --
12. E. Gaggelli, G. Valensin: Oxidative stress in neurodegeneration: targeting mitochondria as a therapeutic aid --
13. Y. Nishsida: The chemical process of oxidative stress by copper(II) and iron(III) ions in several neurodegenerative disorders --
14. O.G. Tsay, K. Kim, D.G. Churchil: Metal ion role in the CNS under toxic organophosphonate exposure: Traces of understanding and various open questions --
15. S. Casito, M. Aschner: Heavy metals, behavior and neurodegeneration: Using C elegans to untangle a can of warms --
16. C. Kallay et al.: The effect of point mutations on copper(II) complexes with peptide fragments encompassin the 106-114 region of human prion protein --
17. E. Sija et al.: Interactions of pyridinecarboxylix acid chelators with brain metal ions: Cu(II), Zn(II), Al(III) --
18. S. Bohic et al.: Spatially resolved imaging methods to probe metals in brain --
19. Y. Ha, O. Tsay, D.G. Churchil: ICP-MS for the neurodegenerative and brain sciences.
Responsibility: Wolfgang Linert, Henryk Kozlowski, editors.
More information:

Abstract:

This book explores key topics in the area of metal ions in the brain, focusing on the role of metal ions in neurological systems by describing their advantageous functions in brain activity as well  Read more...

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