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MHC class I antigens in malignant cells : immune escape and response to immunotherapy

저자: Natalia Aptsiauri; Angel Miguel Garcia-Lora; Teresa Cabrera
출판사: New York, NY : Springer, ©2013.
시리즈: SpringerBriefs in cancer research, 6.
판/형식:   전자도서 : 문서 : 영어모든 판과 형식 보기
데이터베이스:WorldCat
요약:
Abnormal expression of MHC class I molecules in malignant cells is a frequent occurrence that ranges from total loss of all class I antigens to partial loss of MHC specific haplotypes or alleles. Different mechanisms are described to be responsible for these alterations, requiring different therapeutic approaches. A complete characterization of these molecular defects is important for improvement of the strategies  더 읽기…
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장르/형태: Electronic books
자료 유형: 문서, 인터넷 자료
문서 형식: 인터넷 자원, 컴퓨터 파일
모든 저자 / 참여자: Natalia Aptsiauri; Angel Miguel Garcia-Lora; Teresa Cabrera
ISBN: 9781461465430 1461465435 1299693784 9781299693784
OCLC 번호: 829679127
설명: 1 online resource.
내용: Overview of MHC Class I Antigens --
HLA Class I Expression in Human Cancer --
MHC Class I Expression in Experimental Mouse Models of Cancer: Immunotherapy of Tumors with Different MHC-I Expression Patterns --
Potential Therapeutic Approaches for Increasing Tumor Immunogenicity by Upregulation of Tumor HLA Class I Expression --
Conclusions.
일련 제목: SpringerBriefs in cancer research, 6.
책임: Natalia Aptsiauri, Angel Miguel Garcia-Lora, Teresa Cabrera.
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초록:

This book discusses abnormal expression of MHC class I molecules in malignant cells, explaining how MHC class 1 is expressed, and its role in tumor progression. Includes new discoveries by the  더 읽기…

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