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Microarray Innovations : Technology and Experimentation.

Author: Gary Hardiman
Publisher: Hoboken : CRC Press, 2009.
Series: Drug Discovery Series, v. 11.
Edition/Format:   eBook : Document : EnglishView all editions and formats
Summary:
Microarray technologies and applications have evolved steadily with increasing content and better analytical methodologies. This compendium covers improvements in automation, various substrates for printing arrays, platform comparisons and contrasts, experimental design, data normalization and mining schemes, and epigenomic array studies.
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Genre/Form: Electronic books
Additional Physical Format: Print version:
Hardiman, Gary.
Microarray Innovations : Technology and Experimentation.
Hoboken : CRC Press, ©2009
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Gary Hardiman
ISBN: 9781420094510 1420094513
OCLC Number: 781358744
Description: 1 online resource (362 pages).
Contents: Front cover; Contents; Preface; Acknowledgments; Editor; Contributors; Summary of Chapters; Chapter 1. Introduction to Gene Expression Profiling with Dna Microarray Technology; Chapter 2. Introduction to Large-Scale Gene Expression Data Analysis; Chapter 3. The Statistical Design and Analysis of Gene Expression Data; Chapter 4. Laboratory Automation for Microarray Experimentation; Chapter 5. How to Evaluate a Microarray Scanner; Chapter 6. The Role of Substrates in Microarray Experimentation and How to Choose the Correct Coating for Microarraying. Chapter 7. Toward Highly Efficient Automated HybridizationsChapter 8. Characterization of Microarray Hybridization Stoichiometry*; Chapter 9. Data Normalization Selection; Chapter 10. Methods for Assessing Microarray Performance; Chapter 11. Comparison of Different Normalization Methods for Applied Biosystems Expression Array System; Chapter 12. A Systematic Comparison of Gene Expression Measurements across Different Hybridization- Based Technologies; Chapter 13. Dna Methylation Arrays: Methods and Analysis; Chapter 14. Electronic Microarrays: Progress toward Dna Diagnostics. Chapter 15. New Applications for MicroarraysChapter 16. Development of an Oligonucleotide Microarray for Mutational Analysis Using Single or Multiple Sample Hybridization; Chapter 17. Development of an Integrated Molecular Diagnostics Test to Identify Respiratory Viruses; Chapter 18. Microarrays in Neuroscience; Chapter 19. Optimization of Protein Array Fabrication for Establishing High-Throughput Ultra-Sensitive Microarray Assays for Cancer Research; Index; Back cover.
Series Title: Drug Discovery Series, v. 11.

Abstract:

Microarray technologies and applications have evolved steadily with increasing content and better analytical methodologies. This compendium covers improvements in automation, various substrates for printing arrays, platform comparisons and contrasts, experimental design, data normalization and mining schemes, and epigenomic array studies.

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