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Microbial glycobiology : structures, relevance and applications

Author: Anthony P Moran; Otto Holst; Patrick J Brennan, Ph. D.; Mark von Itzstein
Publisher: Amsterdam ; Boston : Academic Press/Elsevier, ©2009.
Edition/Format:   eBook : Document : English : 1st edView all editions and formats
Summary:
This book presents in an easy-to-read format a summary of the important central aspects of microbial glycobiology, i.e. the study of carbohydrates as related to the biology of microorganisms. Microbial glycobiology represents a multidisciplinary and emerging area with implications for a range of basic and applied research fields, as well as having industrial, medical and biotechnological implications. Key Features  Read more...
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Genre/Form: Electronic books
Field guides
Identification
Additional Physical Format: Print version:
Microbial glycobiology.
Amsterdam ; Boston : Academic Press/Elsevier, ©2009
(OCoLC)432405794
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Anthony P Moran; Otto Holst; Patrick J Brennan, Ph. D.; Mark von Itzstein
ISBN: 9780080923246 0080923240 9780123745460 0123745462
OCLC Number: 608435121
Reproduction Notes: Electronic reproduction. [S.l.] : HathiTrust Digital Library, 2010. MiAaHDL
Description: 1 online resource (xviii, 1000 pages, [16] pages of plates) : illustrations (some color)
Details: Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002.
Contents: Part I. Microbial glycolipids, glyoproteins and glycopolymers€ 1. Overview of the glycosylated components of the bacterial cell wall€€ 2. Bacterial cell wall envelope peptidoglycan€€ 3. Core oligosaccharide and lipid A components of lipopolysaccharides€€ 4. O-Specific polysaccharides of Gram-negative bacteria€€ 5. Teichoic acids, lipoteichoic acids, and related cell wall glycopolymers of Gram-positive bacteria€€ 6. Bacterial capsular polysaccharides and exopolysaccharides€€ 7. Bacterial surface layer glycoproteins and "non-classical" secondary cell wall polymers€€ 8. Glycosylation of bacterial and archaeal flagellins€€ 9. Glycosylated components of the mycobacterial cell wall: structure and function€€ 10. Glycoconjugate structure and function in fungal cell walls€€ 11. Cytoplasmic carbohydrate molecules: trehalose and glycogen€€ 12. Glycosylated compounds of parasitic protozoa€€ 13. Analytical approaches towards the structural characterization of microbial wall glycopolymers€€ 14. Single-molecule characterization of microbial polysaccharides€€ 15. Viral surface glycoproteins in carbohydrate recognition: structure and modeling€Part II. Synthesis of microbial glycosylated components; A. Biosynthesis and biosynthetic processes€ 16. Biosynthesis of bacterial peptidoglycan€€ 17. Biosynthesis and membrane assembly of lipid A€€ 18. Biosynthesis of O-antigen chains and assembly€€ 19. Biosynthesis of cell wall teichoic acid polymers€€ 20. Biosynthesis and assembly of capsular polysaccharides€€ 21. Biosynthesis of the mycobacterial cell envelope components€€ 22. Biosynthesis of fungal and yeast glycans€B. Chemical synthesis€€ 23. Chemical synthesis of bacterial lipid A€€ 24. Chemical synthesis of the core oligosaccharide of bacterial lipopolysaccharide€€ 25. Chemical synthesis of lipoichoic acid and derivatives€€ 26. Chemical synthesis of parasitic glycoconjugates and phosphoglycans€ Part III. Microbe-host glycosylated interactions€€ 27. Bacterial lectin-like interactions in cell recognition and adhesion€€ 28. Lectin-like interactions in virus-cell recognition: human immunodeficiency virus and C-type lectin interactions€€ 29. Sialic acid-specific microbial lectins€€€ 30. Bacterial toxins and their carbohydrate receptors at the host-pathogen interface€€ 31. Toll-like receptor recognition of lipoglycans, glycolipids and lipopeptides€€ 32. NOD receptor recognition of peptidoglycan€€ 33. Microbial interaction with mucus and mucins€€ 34. Mannose-fucose recognition by DC-SIGN€€ 35. Host surfactant proteins in microbial recognition€€ 36. T-cell recognition of microbial lipoglycans and glycolipids€ Part IV. Biological relevance of microbial glycosylated components; A. Environmental relevance€€ 37. Extracellular polymeric substances in microbial biofilms€€ 38. Physico-chemical properties of microbial glycopolymers€€ 39. Microbial biofilm-related polysaccharides in biofouling and corrosion€€ 40. Microbial glycosylated components in plant disease€€B. Medical relevance€€ 41. Antigenic variation of microbial surface glycosylated molecules€€ 42. Phase variation of bacterial surface glycosylated molecules in immune evasion€€ 43. Molecular mimicry of host glycosylated structures by bacteria€€ 44. Role of microbial glycosylation in host cell invasion€ Part V. Biotechnological and medical applications€€ 45. Exopolysaccharides produced by lactic acid bacteria in food and probiotic applications€€ 46. Industrial exploitation by genetic engineering of bacterial glycosylation systems€€ 47. Glycomimetics as inhibitors in anti-infection therapy€€ 48. Bacterial polysaccharide vaccines: glycogonjugates and peptide-mimetics€€ 49. Immunomodulation by zwitterionic polysaccharides€€ 50. Future potential of glycomics in microbiology and infectious diseases€
Responsibility: editor-in-chief, Anthony P. Moran ; editors, Otto Holst, Patrick J. Brennan, Mark von Itzstein.

Abstract:

Presents a summary of the important central aspects of microbial glycobiology, the study of carbohydrates as related to the biology of microorganisms.  Read more...

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