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Microvascular research : [biology and pathology]

Author: David Shepro
Publisher: Amsterdam ; Boston : Elsevier Academic Press, ©2006.
Edition/Format:   eBook : Document : EnglishView all editions and formats
Summary:
The microvasculature refers to the smallest blood vessels, arterial and venous, that nurture the tissues of each organ. Apart from transport, they also contribute to the systematic regulation of the body. In everyday terminology, the microcirculation is ""where the action is."" Microcirculation is directly involved in such disease states as Alzheimers, inflammation, tumor growth, diabetic retinopathy, and wound  Read more...
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Genre/Form: Electronic books
Additional Physical Format: Print version:
Microvascular research.
Amsterdam ; Boston : Elsevier Academic Press, ©2006
(DLC) 2005024255
(OCoLC)61456524
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: David Shepro
ISBN: 9780080455037 0080455034
OCLC Number: 180773509
Notes: Subtitle from covers.
Description: 1 online resource (2 volumes [69] pages of plates) : illustrations (some color)
Contents: Cover --
Foreword I --
Foreword II --
Introduction --
Editorial Board Members --
Contributors --
Contents --
CHAPTER 1 Endothelin in the Microvasculature --
CHAPTER 2 Control of Cell Motility by the Cytoskeleton and Extracellular Matrix --
CHAPTER 3 Ultrastructural Morphometry of Capillary Basement Membrane Thickness --
CHAPTER 4 IL-7 Receptor and Microvascular Endothelial Cells --
CHAPTER 5 Matrix Metalloproteinases, Tissue Inhibitors of Metalloproteinases, and the Microvasculature --
CHAPTER 6 Matrix Metalloproteinases and Their Inhibitors --
CHAPTER 7 VEGF-A and Its Isoforms --
CHAPTER 8 Ephrins and the Unveiling of Distinct Arterial and Venous Microcirculations --
CHAPTER 9 Endothelial Heterogeneity --
CHAPTER 10 Portholes on a Vessel: Endothelial Fenestrae --
CHAPTER 11 Neuropilins and the Vasculature --
CHAPTER 12 Receptor Tyrosine Kinase Signal Transduction in the Microvasculature --
CHAPTER 13 Eicosanoids and the Pulmonary Microvasculature --
CHAPTER 14 Role of platelet-derived growth factors in the microvasculature --
CHAPTER 15 Basic Concepts of Intussusceptive Angiogenesis --
CHAPTER 16 Vascular Permeability Factor/Vascular Endothelial Growth Factor (VPF/VEGF, VEGF-A) --
CHAPTER 17 Endothelial Progenitor Cells, Vasculogenesis, and Their Contribution to New Blood Vessel Formation in the Adult --
CHAPTER 18 Pericytes and Microvascular Morphogenesis --
CHAPTER 19 PDGF-B and Pericyte Recruitment --
CHAPTER 20 VEGF Regulation of Morphogenesis --
CHAPTER 21 The Two-Phase Model for Angiogenesis Regulation by the Extracellular Matrix --
CHAPTER 22 Pericytes and Glial Cells and Vascular Development --
CHAPTER 23 Hemangioma: A Model System to Study Growth and Regression of Blood Vessels --
CHAPTER 24 Window Models --
CHAPTER 25 The Cremaster Muscle for Microcirculatory Studies --
CHAPTER 26 Zebrafish: A Model for Studying Microvascular Development and Function --
CHAPTER 27 The Significance of the Nail Fold in Clinical and Experimental Studies --
CHAPTER 28 Capillaries in the Chicken Chorioallantoic Membrane --
CHAPTER 29 The Cremaster Muscle as a Microvascular Research Model --
CHAPTER 30 The Hamster Cheek Pouch as a Research Model of Inflammation --
CHAPTER 31 Regulation of Microvascular Permeability --
CHAPTER 32 Regulation of Vascular Endothelial Cell Signal Transduction and Phenotype by Mechanical Factors --
CHAPTER 33 Autacoid Production by Hemodynamic Forces --
CHAPTER 34 Ion Channels and Arteriolar Tone --
CHAPTER 35 Roles of Nitric Oxide in the Microcirculation --
CHAPTER 36 Rheology of Blood Flow in the Microcirculation --
CHAPTER 37 Endothelial Ca2+ and Endothelium-Derived Hyperpolarizing Factor (EDHF)-Mediated Vasodilatation --
CHAPTER 38 Role of the Endothelial Cell Cytoskeleton in Microvascular Function --
CHAPTER 39 Microvascular Permeability --
CHAPTER 40 TNF-a-Induced Pulmonary Endothelial Permeability: The Role of the Microtubule Cytoskeleton --
CHAPTER 41 Vasoactive Signals and Pericyte Function in the Retina --
CHAPTER 42 Regulation of Microvascular Hydraulic Conductivity --
CHAPTER 43 The Role of Gap Junctions in the Regulation of Arteriolar Tone --
CHAPTER 44 Vascular Control Mechanisms in Skeletal Muscle --
CHAPTER 45 Protein Kinases and Microvascular Permeability --
CHAPTER 46 Vesiculo-vacuolar Organelles Are Perm.
Responsibility: editor-in-chief, David Shepro.

Abstract:

The microvasculature refers to the smallest blood vessels, arterial and venous, that nurture the tissues of each organ. Apart from transport, they also contribute to the systematic regulation of the body. In everyday terminology, the microcirculation is ""where the action is."" Microcirculation is directly involved in such disease states as Alzheimers, inflammation, tumor growth, diabetic retinopathy, and wound healing- plus cardiovascular fitness is directly related to the formation of new capillaries in large muscles. Microvascular Research is the first book devoted exclusively to this vi.

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