| Contents: |
Section I. Mitochondrial structure and function. Mitochondrial DNA structure and function / Carlos T. Moraes ... [et al.]. Oxidative phosphoylation: structure, function, and intermediary metabolism / Simon J.R. Heales, Matthew E. Gegg, and John B. Clark. Import of mitochondrial proteins / Matthias F. Bauer, Sabine Hofmann, and Walter Neupert --
Section II. Primary respiratory chain disorders. Mitochondrial disorders of the nervous system: clinical biochemical, and molecular genetic features / Dominic Thyagarajan and Edward Byrne --
Section III. Secondary respiratory chain disorders. Friedrich's ataxia / J.M. Cooper and J.L. Bradley. Wilson's disease / C.A. Davie and A.H.V. Schapira. Hereditary spastic paraplegia / Christopher J. McDermott and Pamela J. Shaw. Cytochrome c oxidase deficiency / Giacomo P. Comi ... [et al.] --
Section IV. Toxin-induced mitochondrial dysfunction / Susan E. Browne and M. Flint Beal --
Section V. Neurodegenerative disorders. Parkinson's disease / L.V.P. Korlipara and A.H.V. Schapira. Huntington's disease: the mystery unfolds? / Åsa Petersén and Patrik Brundin. Mitochondria in Alzheimer's disease / Russell H. Swerdlow and Stephen J. Kish. Contributions of mitochondrial alterations, resulting from bad genes and a hostile environment, to the pathogenesis of Alzheimer's disease / Mark P. Mattson. Mitochondria and amyotrophic lateral sclerosis / Richard W. Orrell and Anthony H.V. Schapira --
Section VI. Models of mitochondrial disease / Danae Liolitsa and Michael G. Hanna --
Section VII. Defects of [beta]-oxidation including carnitine deficiency / K. Barlett and M. Pourfarzam --
Section VIII. Mitochondrial involvement in aging. The mitochondrial theory of aging: involvement of mitochondrial DNA damage and repair / Nadja C. de Souza-Pinto and Vilhelm A. Bohr. |
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