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Mitochondrial function. Part B : mitochondrial protein kinases, protein phosphatases and mitochondrial diseases

Author: William S Allison; Anne N Murphy
Publisher: San Diego, Calif. : Academic Press/Elsevier, ©2009.
Series: Methods in enzymology, v. 457.
Edition/Format:   eBook : Document : EnglishView all editions and formats
Database:WorldCat
Summary:
The second of two new volumes covering mitochondria, this volume presents methods that have been developed to assess the number and function of nuclear-encoded proteins in the mitochndrion. These diverse chapters focus on regulation of mitochondrial function and mitochondrial diseases, including a section emphasizing the mitochondrial defects associated with type-2 diabetes. The critically acclaimed laboratory  Read more...
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Genre/Form: Electronic books
Additional Physical Format: Print version:
Mitochondrial function. Part B.
San Diego, Calif. : Academic Press/Elsevier, ©2009
(OCoLC)326878769
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: William S Allison; Anne N Murphy
ISBN: 9780080923505 008092350X 9780123746221 0123746221
OCLC Number: 297146013
Description: 1 online resource (liii, 519 pages) : illustrations.
Contents: Defining the Mitochondrial Proteome 1. Method to define the mammalian mitochondrial proteome; V. Mootha 2. Proteome Characterization of Mouse Brain Mitochondria Using Electrospray Ionization Tandem Mass Spectrometry; X.Fang and C. S. Lee 3. Method to analyze tissue heterogeneity of the mammalian mitochondrial proteome; R. S. Balaban 4. Predicting proteomes of mitochondria and related organelles from genomic and expressed sequence tag data; D. Gaston, A. Tsausis and A. Roger 5. MitoP2: the mitochondrial proteome database; H. Prokisch Post-Translational Modifications of Mitochondrial Proteins 6. Reversible protein acetylation in mitochondria; E. Verdin 7.Post-translational modifications of rat liver mitochondria outer membrane proteins' C. L. Hoppel 8.Characterization of a novel ser/thr protein phosphatase in mitochondria; Y. Wang 9. R. Rizzuto 10.Selective enrichment in phosphopeptides for the identification of phosphorylated mitochondrial proteins; G. Pocsfalvi 11. Isolation of Regulatory-competent, Phosphorylated Cytochrome c and Cytochrome c Oxidase; M. Huttemann 12. Identification of tyrosine phosphorylated proteins by Src kinases in rat brain; M. Salvi 13. Detection of a mitochondrial kinase complex that mediates an ERK-dependent phosphorylation of mitochondrial protein in steroid biosynthesis; E. J. Podesta 14. Dual specific phosphatases 18 and 21 target to opposing sides of the mitochondrial inner membrane; J. Rardin & J. E. Dixon 15.M. A. Kostiuk and B. O. Keller: "Isolation and identification of palmitoylated proteins in mitochondria using a chemical biology approach; L. G. Berthiaume Mitochondrial Dynamics 16.Mitochondrial fusion and movement using photoactivatable GFP; O. Shirihai 17. Regulation of mitochondrial fission and fusion by kinase and phosphatase activities. no title yet; S. Strack 18. Mitochondrial movement and synaptic function in Drosophila; T. L. Schwarz 19. The use of yeast and a novel biosensor to study mitochondrial ion transport, swelling, and mitophagy; R. J. Scheweyen 20.Complete Exchange of mtDNA's between Mouse Cells for Testing the Effects of mtDNA on Tumor Phenotypes; J. Hayashi Mitochondrial Function in Pancreatic Beta Cells 21. Coupling efficiency INS-1E cells; M. D. Brand and C. Affourtit 22. Methods in the study of substrate-specific differences on mitochondrial function mediating insulin secretion from pancreatic beta cells; B. E. Corkey 23. Knocking down of UCP 2 in animal models of obesity; L. A.Velloso 24.Roles of the cytosolic and mitochondrial forms of the malic enzyme on insulin secretion; G. W. Cline 25. Altered regulation of the PINK1 locus as a link between type 2 diabetes and neurodegeneration; J. A. Timmons 26. Insulin secretion from pancreatic beta cells is affected deletion of the nicotinamide nucleotide transhydrogenase; R. D. Cox 27. Determination of oxidative capacity and mitochondrial function in insulin resistance and type 2 diabetes; G. Shulman et al 28.Mitochondrial ATP production rate; K. S. Nair
Series Title: Methods in enzymology, v. 457.
Responsibility: edited by William S. Allison and Anne N. Murphy.

Abstract:

Presents methods that have been developed to assess the number and function of nuclear-encoded proteins in the mitochndrion. This work focuses on regulation of mitochondrial function and  Read more...

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