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Modern methods of drug discovery

Author: A Hillisch; R Hilgenfeld
Publisher: Basel ; Boston : Birkhäuser Verlag, ©2003.
Series: EXS, 93.
Edition/Format:   Print book : EnglishView all editions and formats
Summary:

As a consequence, researchers and project managers in the pharmaceutical industry should have a solid knowledge of the more important methods available to drug discovery, because it is the rapidly  Read more...

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Details

Material Type: Internet resource
Document Type: Book, Internet Resource
All Authors / Contributors: A Hillisch; R Hilgenfeld
ISBN: 376436081X 9783764360818
OCLC Number: 50606430
Description: ix, 292 pages : illustrations ; 24 cm.
Contents: 1. Modern methods of drug discovery: An introduction / Helmut Giersiefen, Rolf Hilgenfeld and Alexander Hillisch --
2. Proteomics / Martin J. Page, Chris Moyses, Mary J. Cunningham, Gordon Holt and Alastair Matheson --
3. Bioinformatics / David B. Jackson, Eric Minch and Robin E. Munro --
4. High-throughput screening technologies / Ralf Thiericke --
5. Natural products for lead identification: Nature is a valuable resource for providing tools / Susanne Grabley and Isabel Sattler --
6. Combinatorial chemistry: Mixture-based combinatorial libraries of acyclic and heterocyclic compounds from amino acids and short peptides / Adel Nefzi, John M. Ostresh and Richard A. Houghten --
7. Computational approaches towards the quantification of molecular diversity and design of compound libraries / Hans Matter --
8. role of protein 3D-structures in the drug discovery process / Alexander Hillisch and Rolf Hilgenfeld --
9. NMR-based screening methods for lead discovery / Martin Vogtherr and Klaus Fiebig --
10. Structure-based design of combinatorial libraries / John H. van Drie, Douglas C. Rohrer, James R. Blinn and Hua Gao --
11. 3D QSAR in modern drug design / Glen E. Kellogg and Simon F. Semus --
12. Physicochemical concepts in drug design / Han van de Waterbeemd --
13. Computer-aided prediction of drug toxicity and metabolism / Mark T.D. Cronin.
Series Title: EXS, 93.
Responsibility: edited by A. Hillisch and R. Hilgenfeld.
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