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Molecular analysis and genome discovery

Author: Ralph Rapley; Stuart Harbron
Publisher: Chichester, West Sussex, England ; Hoboken, N.J. : J. Wiley, ©2004.
Edition/Format:   Print book : EnglishView all editions and formats
Summary:
Provides a comprehensive overview of recent developments in the area of molecular based diagnostics (including nucleic acids, biosensors and immunoessays) of disease markers. It also covers the impact of techniques such as in vitro nucleic acid amplifications (e.g. PCR) and other amplification methods, as well as gene and biochip production and automated techniques such as fluorescent sequencing. The book discusses  Read more...
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Genre/Form: Aufsatzsammlung
Additional Physical Format: Online version:
Molecular analysis and genome discovery.
Chichester, West Sussex, England ; Hoboken, N.J. : J. Wiley, ©2004
(OCoLC)608748510
Material Type: Internet resource
Document Type: Book, Internet Resource
All Authors / Contributors: Ralph Rapley; Stuart Harbron
ISBN: 0471498475 9780471498476 0471499196 9780471499190
OCLC Number: 54073950
Description: xv, 372 pages : illustrations ; 24 cm
Contents: Pharmacogenetics and pharmacogenomics: an overview / W. Kalow --
Quantitative TaqMan real-time PCR: diagnostic and scientific applications / Jörg Dötsch, Ellen Schoof, and Wolfgang Rascher --
Hybridization probes for quantitative PCR / Elaine Lyon --
An overview of genotyping and single nucleotide polymorphisms (SNP) / Ivo Glynne Gut --
High-throughput mutation screening / Paal Skytt Andersen and Lars Allan Larsen --
Determination of nucleic acid sequence by pyrosequencing / Elaine Elahi and Mostafa Ronaghi --
An introduction to DNA chips / Magdalena Gabig-Ciminska and Andrzej Ciminski --
Overview of microarrays in genomic analysis / Janette K. Burgess --
Overview of differential gene expression by high-throughput analysis / Kin-Ying To. Aptamers: powerful molecular tools for therapeutics and diagnostics / Eva Baldrich i Rubio, Monica Campos i Homs, and Ciara K. O'Sullivan --
Chip-based proteomics technology / Mikhail Soloviev, Richard Barry, and Jon Terrett --
Infectomics overview: holistic and integrative studies of infectious diseases / Sheng-He Huang and Ambrose Jong --
The drug discovery process / Roberto Solari --
Structure-based drug discovery / Chen-Chen Kan, Kevin Hambly, and Derek A. Debe --
Protein interaction-targeted drug discovery / Gary Hudes, Sanjay Menon, and Erica A. Golemis --
Overview of quantitative structure-activity relationships (QSAR) / David A. Winkler.
Responsibility: edited by Ralph Rapley and Stuart Harbron.
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Abstract:

Provides a comprehensive overview of the developments in the area of molecular based diagnostics of disease markers. This book covers the impact of techniques such as in vitro nucleic acid  Read more...

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"...aims to bring together genomics and drug discovery, and to show how rapid advances in molecular analysis are bringing new tools and approaches to genome discovery." (Genomics & Proteomics, Read more...

 
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