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Molecular Genetics and Therapy of Leukemia

Author: Emil J Freireich; Hagop Kantarjian
Publisher: Boston, MA : Springer US, 1996.
Series: Cancer treatment and research, 84.
Edition/Format:   eBook : Document : EnglishView all editions and formats
Summary:
Leukemia is a malignant disease which continues to play a cutting edge role in the discovery of new basic knowledge about the malignant process and about the potential for controlling these malignant diseases. Molecular Genetics and Therapy of Leukemia presents contributions by leading investigators and scientific contributors to such topics as chromosome 16, chromosome 5, the BCL-2 gene, 11q23 breakpoint leukemias,  Read more...
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Details

Genre/Form: Electronic books
Additional Physical Format: Print version:
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Emil J Freireich; Hagop Kantarjian
ISBN: 9781461312611 1461312612
OCLC Number: 852789069
Description: 1 online resource (352 pages).
Contents: 1. Molecular Genetics of Inversion 16 Leukemia: Implications for Leukemogenesis --
2. Deletion of Chromosome 5 (5q- ) in Leukemia: Current Knowledge --
3. Bcl-2 Family Proteins and the Regulation of Programmed Cell Death in Leukemia and Lymphoma --
4. MLL Fusion Genes in the 11q23 Acute Leukemias --
5. The c-myb Protooncogene: A Novel Target for Human Gene Therapy --
6. The Role of p53 in Malignancy --
7. Primitive Hematopoietic Stem and Progenitor Cells in Human Umbilical Cord Blood: An Alternative Source of Transplantable Cells --
8. Detection of Minimal Residual Disease in ALL: Biology, Methods, and Applications --
9. Interleukin-6: Biologic Properties and Role in Lymphoproliferative Disorders --
10. Autologous Bone Marrow Transplantation for Leukemia and Lymphoma --
11. Retinoblastoma Gene in Malignancy --
12. Treatment of Relapse After Allogeneic Bone Marrow Transplantation --
13. Acute Lymphocytic Leukemia: A Comprehensive Review with Emphasis on Biology and Therapy.
Series Title: Cancer treatment and research, 84.
Responsibility: edited by Emil J. Freireich, Hagop Kantarjian.

Abstract:

Leukemia is a malignant disease which continues to play a cutting edge role in the discovery of new basic knowledge about the malignant process and about the potential for controlling these malignant diseases. Molecular Genetics and Therapy of Leukemia presents contributions by leading investigators and scientific contributors to such topics as chromosome 16, chromosome 5, the BCL-2 gene, 11q23 breakpoint leukemias, the p-53 suppressor gene and oncogene, hematopoietic stem cells, cytokines, detection of minimal residual disease in acute lymphoblastic leukemia, autologous marrow transplantation, the retinoblastoma gene, allogeneic bone marrow transplant and chemotherapy of acute lymphoblastic leukemia.

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