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Molecular genetics of inflammatory bowel disease

Author: Mauro D'Amato; John D Rioux
Publisher: New York : Springer, [2013]
Edition/Format:   Print book : EnglishView all editions and formats

Molecular Genetics of Inflammatory Bowel Disease


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Document Type: Book
All Authors / Contributors: Mauro D'Amato; John D Rioux
ISBN: 9781461482550 1461482550
OCLC Number: 874092920
Description: xiii, 343 pages : illustrations
Contents: Part 1: The Foundation of IBD Genetics, Human and Animal Studies.- A Primer on IBD: Phenotypes, Diagnosis, Treatment and Clinical Challenges.- Genetic Epidemiology of Inflammatory Bowel Disease, Early Twin and Family Studies.- Insights from Recent Advances in Animal Models of Inflammatory Bowel Disease.- Part Two: The Genetic and Molecular Makeup of Inflammatory Bowel Disease.- Complex Disease Genes and their Discovery.- The Genetics of Crohn's Disease.- Genetics of Ulcerative Colitis.- Genetic Overlap between Inflammatory Bowel Disease and Other Diseases.- Molecular Profiling of IBD Subtypes/Response to Therapy.- Epigenetics of Inflammatory Bowel Disease.- Part 3: Pathogenetic Pathways in Inflammatory Bowel Disease.- Nod1 and Nod2 and the Immune Response to Bacteria.- The IL-23-Th17 Axis in Intestinal Inflammation.- Inflammatory Bowel Disease at the Intersection of Autophagy and Immunity: Insights from Human Genetics.- The Epithelial Barrier.- Host Interactions with Bacteria: From "Entente Cordiale" to "Casus Belli".- Cytokines in Inflammatory Bowel Disease.- Part 4: Concluding Remarks and Future Perspectives.- Towards Personalized Therapy in Inflammatory Bowel Disease.- Index.
Responsibility: Mauro D'Amato, John D. Rioux, editors.


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