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Molecular Pathogenesis of Colorectal Cancer

Author: Ph D Kevin M Haigis
Publisher: New York, NY : Springer, 2013.
Series: SpringerLink : Bücher
Edition/Format:   eBook : EnglishView all editions and formats
Database:WorldCat
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Material Type: Internet resource
Document Type: Internet Resource
All Authors / Contributors: Ph D Kevin M Haigis
ISBN: 9781461484127 146148412X
OCLC Number: 865039369
Description: Online-Ressource (VIII, 316 p. 30 illus., 29 illus. in color, online resource)
Contents: Preface --
The Genetics of Colorectal Cancer --
Molecular Mechanisms of Colorectal Carcinogenesis --
The association between inflammation and colorectal cancer --
Importance of the niche: Wnt signalling and Stem cell plasticity in intestinal homeostasis and disease --
Mutational activation of KRAS and BRAF in colorectal cancer --
The PI3K pathway in Colorectal Cancers --
TGF-ß signaling pathway and colorectal cancer --
The Clinical Significance of Mutations in Colorectal Cancer --
Colorectal Cancer Genome and Its Implications --
Copy-Number Alterations in the Colorectal Cancer Genome --
Genome-wide association studies in colorectal cancer --
Future prospects for leveraging molecular information in the fight against colorectal cancer --
Index.
Series Title: SpringerLink : Bücher
Responsibility: edited by Kevin M. Haigis, Ph.D.

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