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Molecular Pathogenesis of Colorectal Cancer

Autor: Ph D Kevin M Haigis
Editora: New York, NY : Springer, 2013.
Séries: SpringerLink : Bücher
Edição/Formato   e-book : InglêsVer todas as edições e formatos
Base de Dados:WorldCat
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Tipo de Material: Recurso Internet
Tipo de Documento Recursos de internet
Todos os Autores / Contribuintes: Ph D Kevin M Haigis
ISBN: 9781461484127 146148412X
Número OCLC: 865039369
Descrição: Online-Ressource (VIII, 316 p. 30 illus., 29 illus. in color, online resource)
Conteúdos: Preface --
The Genetics of Colorectal Cancer --
Molecular Mechanisms of Colorectal Carcinogenesis --
The association between inflammation and colorectal cancer --
Importance of the niche: Wnt signalling and Stem cell plasticity in intestinal homeostasis and disease --
Mutational activation of KRAS and BRAF in colorectal cancer --
The PI3K pathway in Colorectal Cancers --
TGF-ß signaling pathway and colorectal cancer --
The Clinical Significance of Mutations in Colorectal Cancer --
Colorectal Cancer Genome and Its Implications --
Copy-Number Alterations in the Colorectal Cancer Genome --
Genome-wide association studies in colorectal cancer --
Future prospects for leveraging molecular information in the fight against colorectal cancer --
Index.
Título da Série: SpringerLink : Bücher
Responsabilidade: edited by Kevin M. Haigis, Ph.D.

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