aller au contenu
Molecular pathogenesis of colorectal cancer Aperçu de cet ouvrage
FermerAperçu de cet ouvrage
Vérification...

Molecular pathogenesis of colorectal cancer

Auteur : Kevin M Haigis
Éditeur : New York : Springer, ©2013.
Édition/format :   Livre imprimé : EnglishVoir toutes les éditions et tous les formats
Base de données :WorldCat
Résumé :
Colorectal cancer has for more than two decades served as the paradigm for the multi-step concept of cancer initiation and progression. Perhaps more than any other organ site, cancer of the colon is extensively characterized at the molecular level. We are now entering a time when molecular classification, rather than histologic classification, of cancer subtypes is driving the development of clinical trials with  Lire la suite...
Évaluation :

(pas encore évalué) 0 avec des critiques - Soyez le premier.

Sujets
Plus comme ceci

 

Trouver un exemplaire dans la bibliothèque

&AllPage.SpinnerRetrieving; Recherche de bibliothèques qui possèdent cet ouvrage...

Détails

Format : Book
Tous les auteurs / collaborateurs : Kevin M Haigis
ISBN : 9781461484110 1461484111
Numéro OCLC : 857961773
Description : viii, 316 pages : illustrations (some color) ; 24 cm
Contenu : Preface.- The Genetics of Colorectal Cancer.- Molecular Mechanisms of Colorectal Carcinogenesis.- The association between inflammation and colorectal cancer.- Importance of the niche: Wnt signalling and Stem cell plasticity in intestinal homeostasis and disease.- Mutational activation of KRAS and BRAF in colorectal cancer.- The PI3K pathway in Colorectal Cancers.- TGF-ss signaling pathway and colorectal cancer.- The Clinical Significance of Mutations in Colorectal Cancer.- Colorectal Cancer Genome and Its Implications.- Copy-Number Alterations in the Colorectal Cancer Genome.- Genome-wide association studies in colorectal cancer.- Future prospects for leveraging molecular information in the fight against colorectal cancer.- Index.
Responsabilité : Kevin M. Haigis, editor.

Résumé :

This book identifies and characterizes targetable oncogenic pathways in colorectal cancer. It explores the current and future prospects for targeting these pathways therapeutically and presents  Lire la suite...

Critiques

Critiques d’utilisateurs
Récupération des critiques de GoodReads...
Récuperation des critiques DOGObooks…

Étiquettes

Soyez le premier.
Confirmez cette demande

Vous avez peut-être déjà demandé cet ouvrage. Veuillez sélectionner OK si vous voulez poursuivre avec cette demande quand même.

Données liées


Primary Entity

<http://www.worldcat.org/oclc/857961773> # Molecular pathogenesis of colorectal cancer
    a schema:Book, schema:CreativeWork ;
   library:oclcnum "857961773" ;
   library:placeOfPublication <http://dbpedia.org/resource/New_York_City> ; # New York
   library:placeOfPublication <http://id.loc.gov/vocabulary/countries/nyu> ;
   schema:about <http://experiment.worldcat.org/entity/work/data/1654673874#Topic/rectum_cancer_diagnosis> ; # Rectum--Cancer--Diagnosis
   schema:about <http://experiment.worldcat.org/entity/work/data/1654673874#Topic/medical_technology> ; # Medical technology
   schema:about <http://experiment.worldcat.org/entity/work/data/1654673874#Topic/pathology_molecular> ; # Pathology, Molecular
   schema:about <http://experiment.worldcat.org/entity/work/data/1654673874#Topic/colorectal_neoplasms> ; # Colorectal Neoplasms
   schema:about <http://experiment.worldcat.org/entity/work/data/1654673874#Topic/colon_anatomy_cancer_diagnosis> ; # Colon (Anatomy)--Cancer--Diagnosis
   schema:about <http://dewey.info/class/616.075/e23/> ;
   schema:about <http://experiment.worldcat.org/entity/work/data/1654673874#Topic/molecular_diagnosis> ; # Molecular diagnosis
   schema:bookFormat bgn:PrintBook ;
   schema:copyrightYear "2013" ;
   schema:datePublished "2013" ;
   schema:description "Colorectal cancer has for more than two decades served as the paradigm for the multi-step concept of cancer initiation and progression. Perhaps more than any other organ site, cancer of the colon is extensively characterized at the molecular level. We are now entering a time when molecular classification, rather than histologic classification, of cancer subtypes is driving the development of clinical trials with emerging targeted therapies. The book will focus on the progression from the identification of mutations that drive colorectal cancer initiation and progression to the search for novel therapies to treat the disease."@en ;
   schema:editor <http://experiment.worldcat.org/entity/work/data/1654673874#Person/haigis_kevin_m> ; # Kevin M. Haigis
   schema:exampleOfWork <http://worldcat.org/entity/work/id/1654673874> ;
   schema:inLanguage "en" ;
   schema:name "Molecular pathogenesis of colorectal cancer"@en ;
   schema:productID "857961773" ;
   schema:publication <http://www.worldcat.org/title/-/oclc/857961773#PublicationEvent/new_york_springer_2013> ;
   schema:publisher <http://experiment.worldcat.org/entity/work/data/1654673874#Agent/springer> ; # Springer
   schema:workExample <http://worldcat.org/isbn/9781461484110> ;
   wdrs:describedby <http://www.worldcat.org/title/-/oclc/857961773> ;
    .


Related Entities

<http://dbpedia.org/resource/New_York_City> # New York
    a schema:Place ;
   schema:name "New York" ;
    .

<http://experiment.worldcat.org/entity/work/data/1654673874#Person/haigis_kevin_m> # Kevin M. Haigis
    a schema:Person ;
   schema:familyName "Haigis" ;
   schema:givenName "Kevin M." ;
   schema:name "Kevin M. Haigis" ;
    .

<http://experiment.worldcat.org/entity/work/data/1654673874#Topic/colon_anatomy_cancer_diagnosis> # Colon (Anatomy)--Cancer--Diagnosis
    a schema:Intangible ;
   schema:name "Colon (Anatomy)--Cancer--Diagnosis"@en ;
    .

<http://experiment.worldcat.org/entity/work/data/1654673874#Topic/colorectal_neoplasms> # Colorectal Neoplasms
    a schema:Intangible ;
   schema:name "Colorectal Neoplasms"@en ;
    .

<http://experiment.worldcat.org/entity/work/data/1654673874#Topic/molecular_diagnosis> # Molecular diagnosis
    a schema:Intangible ;
   schema:name "Molecular diagnosis"@en ;
    .

<http://experiment.worldcat.org/entity/work/data/1654673874#Topic/pathology_molecular> # Pathology, Molecular
    a schema:Intangible ;
   schema:name "Pathology, Molecular"@en ;
    .

<http://experiment.worldcat.org/entity/work/data/1654673874#Topic/rectum_cancer_diagnosis> # Rectum--Cancer--Diagnosis
    a schema:Intangible ;
   schema:name "Rectum--Cancer--Diagnosis"@en ;
    .

<http://worldcat.org/isbn/9781461484110>
    a schema:ProductModel ;
   schema:isbn "1461484111" ;
   schema:isbn "9781461484110" ;
    .


Content-negotiable representations

Fermer la fenêtre

Veuillez vous identifier dans WorldCat 

Dont have an account? You can easily créez un compte gratuit.