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Molecularly targeted therapy for childhood cancer

Author: Peter J Houghton; Robert Arceci
Publisher: New York : Springer, ©2010.
Edition/Format:   Print book : EnglishView all editions and formats
Summary:

Each chapter will focus on the known molecular characteristics of specific childhood cancers, focusing on how the molecular `drivers' can be exploited from a therapeutic standpoint with currently  Read more...

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Document Type: Book
All Authors / Contributors: Peter J Houghton; Robert Arceci
ISBN: 9780387690605 0387690603 9780387690629 038769062X
OCLC Number: 664325980
Description: xviii, 536 pages : illustrations (some color) ; 24 cm
Contents: Hematologic Malignancies.- The Emerging Era of Targeted Therapy in Childhood Acute Lymphoblastic Leukemia.- Molecular Targeted Therapies in T-Cell Acute Lymphoblastic Leukemia.- Molecularly Targeted Therapy for Infant ALL.- Targeted Therapeutic Approaches for AML.- Acute Promyelocytic Leukaemia.- Down Syndrome and Acute Myeloid Leukemia: An Unique Genetic Sensitivity to Chemotherapy.- Targeting RAS Signaling Pathways in Juvenile Myelomonocytic Leukemia (JMML).- Chronic Myeloid Leukemia: Pathophysiology and Therapeutics.- Molecularly Targeted Therapies in Pediatric Myelodysplastic Syndromes.- New Therapeutic Frontiers for Childhood Non-Hodgkin Lymphoma.- Molecular Targeting of Post-transplant Lymphoproliferative Disorders.- Solid Tumors.- Molecularly Targeted Therapies for Astrocytomas.- Targeted Therapy in Medulloblastoma in Molecularly Targeted Therapy for Childhood Cancer.- Future Treatments of Ependymoma.- Development of Targeted Therapies for Rhabdoid Tumors Based on the Functions of INI1/hSNF5 Tumor Suppressor.- Development of Targeted Therapies for Neurofibromatosis Type 1 (NF1) Related Tumors.- Molecular Therapy for Neuroblastoma.- Ewing's Sarcoma Family of Tumors: Molecular Targets Need Arrows.- Molecular Targeted Therapy for Wilms' Tumor.- Molecular Therapy for Rhabdomyosarcoma.- Molecularly Targeted Therapy for Osteosarcoma: Where Do We Go from Here?.- Nonrhabdomyosarcoma Soft Tissue Sarcoma in Children: Developing New Treatments Based on a Better Understanding of Disease Biology.
Responsibility: Peter J. Houghton, Robert J. Arceci, editors.

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