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Multiple sclerosis : immunology, pathology, and pathophysiology

Author: Robert M Herndon
Publisher: New York, N.Y. : Demos Medical Pub., ©2003.
Edition/Format:   eBook : Document : EnglishView all editions and formats
Summary:
Annotation

This volume provides an overview of MS-related research and will benefit many investigators in the field and help to advance our efforts to cure this, thus far, intractable disease.

Annotation

From historical cases suggestive of multiple sclerosis and the 1838 clinical description of MS to the latest research, Dr. Herndon (neurology, U. of Mississippi Medical Center, Jackson) provides an overview of developments relating to this central nervous system autoimmune disease. In this companion volume to </Multiple sclerosis: diagnosis, medical management, and rehabilitation/> (Demos, 2000), US contributors to 16 chapters offer an overview of advances in the basic sciences and technologies as they pertain to understanding immune responses in MS (e.g., an animal model of demyelinating disease, identification of contributory infectious agents). The final chapter offers hope for remyelination of nerve fibers and recovery of function. Coverage of epidemiology and genetics is acknowledged as minimal. Annotation c. Book News, Inc., Portland, OR (booknews.com).  Read more...

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Genre/Form: Electronic books
Additional Physical Format: Print version:
Multiple sclerosis.
New York, N.Y. : Demos Medical Pub., ©2003
(DLC) 2002015198
(OCoLC)50639312
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Robert M Herndon
ISBN: 9781888799620 1888799625 141755214X 9781417552146 9781934559260 1934559261
OCLC Number: 228129085
Notes: Companion vol. to: Multiple sclerosis: diagnosis, medical management, and rehabilitation / edited by Jack S. Burks and Kenneth P. Johnson.
Description: 1 online resource (xii, 239 pages) : illustrations
Contents: Developments in multiple sclerosis research / Robert M. Herndon --
Morphology of oligodendrocytes and myelin / Robert Skoff --
Astroctes: morphology and function / Robert M. Herndon --
Molecular structure of the myelin membrane / Joyce A. Benjamins --
The nature of immunologic privilege in the central nervous system / Zsuzsa Fabry, Matyas Sandor, Diane Sewell, and Emily Reinke --
Experimental autoimmune encephalomyelitis / LaChelle R. Arredondo, Amy Lovett-Racke, and Michael K. Racke --
Tissue culture studies of demyelination and remyelination / Frederick J. Seil --
Infectious agents and demyelination / John Rose --
Viral demyelinating diseases in experimental animals / Jane E. Libbey and Robert S. Fujinami --
Chlamydia pneumoniae infection and its association with multiple sclerosis / Harold Moses Jr. and Sabramaniam Sriram --
The role of cytokines in multiple sclerosis and experimental allergic encephalomyelitis / Tanuja Chitnis and Samia J. Khoury --
Chemokines and their receptors in multiple sclerosis / Richard M. Ransohoff and William J. Karpus --
Interferons in multiple sclerosis / Suhayl Dhib-Jalbut --
The pathology of multiple sclerosis as revealed by in vivo magnetic resonance-based approaches / Jack H. Simon --
Mechanisms of repair, adaptation, and recovery of function in multiple sclerosis / Robert M. Herndon.
Other Titles: Multiple sclerosis.
Responsibility: Robert M. Herndon, editor.
More information:

Abstract:

Annotation

This volume provides an overview of MS-related research and will benefit many investigators in the field and help to advance our efforts to cure this, thus far, intractable disease.

Annotation

From historical cases suggestive of multiple sclerosis and the 1838 clinical description of MS to the latest research, Dr. Herndon (neurology, U. of Mississippi Medical Center, Jackson) provides an overview of developments relating to this central nervous system autoimmune disease. In this companion volume to </Multiple sclerosis: diagnosis, medical management, and rehabilitation/> (Demos, 2000), US contributors to 16 chapters offer an overview of advances in the basic sciences and technologies as they pertain to understanding immune responses in MS (e.g., an animal model of demyelinating disease, identification of contributory infectious agents). The final chapter offers hope for remyelination of nerve fibers and recovery of function. Coverage of epidemiology and genetics is acknowledged as minimal. Annotation c. Book News, Inc., Portland, OR (booknews.com).

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"The magnetic resonance imaging chapter is a tour de force with excellent breadth and fine illustrations...a valuable resource...pleasing to a wide audience of scientists and academic physicians in Read more...

 
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