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The music of life : biology beyond genes

Author: Denis Noble
Publisher: Oxford OUP 2006.
Edition/Format:   Print book : EnglishView all editions and formats
Summary:
"Drawing on his experiences in his research on the heartbeat, and on evolutionary biology, development, medicine, philosophy, linguistics, and Chinese culture, Noble presents us with a profound and modern reflection on the nature of life."--Jacket.
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Material Type: Internet resource
Document Type: Book, Internet Resource
All Authors / Contributors: Denis Noble
ISBN: 0199228361 : PAP 9780199228362 : PAP 0199295735 9780199295739
OCLC Number: 768644291
Description: 153 pages ; 19 cm
Contents: The CD of life : the genome --
Introducing the Silmans --
DNA-mania --
Problems with genetic determinism --
Origin of the appeal of genetic determinism --
Life is not a protein soup --
Mapping the alternative metaphors --
The organ of 30,000 pipes --
The Chinese emperor and the poor farmer --
The genome and combinatorial explosion --
An organ of 30000 pipes --
The score : is it written down? --
Is the genome the 'book of life'? --
The French bistro omelette --
The ambiguity of language --
The Silmans return --
The conductor : downward causation --
How is the genome played? --
Is the genome a program? --
Control of gene expression --
Downward causation takes many forms --
Other forms of downward causation --
Where is the program of life? --
The rhythm section : the heartbeat and other rhythms --
Beginnings of biological computation --
Reconstructing heart rhythm : the first attempt --
The integrative level of heart rhythm --
Systems biology is not 'vitalism' in disguise --
Nor is it reductionism in disguise --
Other natural rhythms --
The orchestra : organs and systems of the body --
Novartis Foundation debates --
Problems with bottom-up --
Problems with top-down --
Middle-out! --
The organs of the body --
The virtual heart --
Modes and keys : cellular harmony --
The Silmans find some tropical islands --
The Silmans' mistake --
Genetic basis of cell differentiation --
Modes and keys --
Multicellular harmony --
A historical note on 'Lamarckism' --
The composer : evolution --
The Chinese writing system --
Modularity in genes --
Gene-protein networks --
Fail-safe redundancy --
Faustian pacts with the devil --
The logic of life --
The grand composer --
The opera theatre : the brain --
How do we see the world? --
At Aziz' restaurant --
Action and will : a physiologist and a philosopher experiment --
Explanatory shift between levels --
The self is not a neural object --
The deep-frozen brain --
The resurrected self? --
Curtain call : the artist disappears --
Jupitereans --
Role of culture in our view of the self and the brain --
The self as metaphor --
The artist disappears.
Responsibility: Denis Noble.
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Abstract:

What is Life? To answer this question, Denis Noble argues that we must look beyond the gene's eye view. For modern 'systems biology' considers life on a variety of levels, as an intricate web of  Read more...

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highly evocative essay * Steven Poole, The Guardian * Review from previous edition A beautifully written book... After the great successes of molecular biology, the time has come to re-assemble the Read more...

 
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