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NanoCellBiology of secretion : imaging its cellular and molecular underpinnings

저자: Bhanu P Jena; Lloyd L Anderson
출판사: New York : Springer, 2012.
시리즈: SpringerBriefs in biological imaging.
판/형식:   전자도서 : 문서 : 영어모든 판과 형식 보기
데이터베이스:WorldCat
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Understanding live cells at the single molecule level is the most important and single major challenge facing biology and medicine today. Opening with an explanation of Materials and Methods, this  더 읽기…

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장르/형태: Electronic books
추가적인 물리적 형식: Print version:
Jena, Bhanu P.
NanoCellBiology of secretion.
New York : Springer, 2012
(DLC) 2011945438
자료 유형: 문서, 인터넷 자료
문서 형식: 인터넷 자원, 컴퓨터 파일
모든 저자 / 참여자: Bhanu P Jena; Lloyd L Anderson
ISBN: 9781461424383 1461424380
OCLC 번호: 781540178
설명: 1 online resource (xii, 70 p.) : ill. (chiefly col.)
내용: Understanding live cells at the single molecule level is the most important and single major challenge facing biology and medicine today. Over the past 15 years, there has been a renewed understanding of living cells at the molecular level. Atomic Force Microscopy, Laser Force Microscopy, single secretory vesicle patch clamp studies, highresolution electron microscopy, and x-ray diffraction, are some of the tools now being used to unravel the intricacies of a living cell at the molecular level. Opening with an explanation of Materials and Methods, NanoCellBiology then moves through discussions of porosome discovery, calcium and SNARE-induced fusion, and vesicle swelling before winding up in a final chapter of conclusions and future studies. Succinctly packaged as SpringerBrief, this book is a must for those studying or conducting research in cell biology, biochemistry or nanobiology/nanotechnology. This book will be invaluable to faculty & graduate students involved in Nano Courses; Cell Biology Courses; Biophysics Courses; and Biochemistry Courses as well as practicing Cell Biologists, Biochemists and BioPhysicists. Table of contetns: Introduction.- Materials & Methods.- Porosome Discovery.- Calcium & SNARE-Induced Membrane Fusion.- SNAREs need to reside in opposing membrane.- Membrane curvature dictates SNARE size.- Disassembly of membrane-associated SNARE complex.- CD spectroscopy confirm membrane requirement for t-/v-SNARE assembly.- SNAREs bring opposing bilayers closer for calcium bridging.- Membrane lipids influence SNARE complex assembly-disassembly.- Vesicle swelling and content expulsion during cell secretion.- Secretory vesicle swelling is required for intravesicular content expulsion.- Molecular mechanism of secretory vesicle swelling.- Presence of beta receptors at the secretory vesicle membrane.- Conclusion and future studies.
일련 제목: SpringerBriefs in biological imaging.
다른 제목 Nano cell biology of secretion
책임: Bhanu P. Jena ; foreword by Lloyd L. Anderson.
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