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NanoCellBiology of secretion : imaging its cellular and molecular underpinnings

Autor: Bhanu P Jena; Lloyd L Anderson
Editora: New York : Springer, 2012.
Séries: SpringerBriefs in biological imaging.
Edição/Formato   e-book : Documento : InglêsVer todas as edições e formatos
Resumo:
Understanding live cells at the single molecule level is the most important and single major challenge facing biology and medicine today. Over the past 15 years, there has been a renewed understanding of living cells at the molecular level. Atomic Force Microscopy, Laser Force Microscopy, single secretory vesicle patch clamp studies, highresolution electron microscopy, and x-ray diffraction, are some of the tools  Ler mais...
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Detalhes

Gênero/Forma: Electronic books
Formato Físico Adicional: Print version:
Jena, Bhanu P.
NanoCellBiology of secretion.
New York : Springer, 2012
(DLC) 2011945438
Tipo de Material: Documento, Recurso Internet
Tipo de Documento Recursos de internet, Arquivo de computador
Todos os Autores / Contribuintes: Bhanu P Jena; Lloyd L Anderson
ISBN: 9781461424383 1461424380
Número OCLC: 781540178
Descrição: 1 online resource (xii, 70 pages) : illustrations (chiefly color).
Conteúdos: Understanding live cells at the single molecule level is the most important and single major challenge facing biology and medicine today. Over the past 15 years, there has been a renewed understanding of living cells at the molecular level. Atomic Force Microscopy, Laser Force Microscopy, single secretory vesicle patch clamp studies, highresolution electron microscopy, and x-ray diffraction, are some of the tools now being used to unravel the intricacies of a living cell at the molecular level. Opening with an explanation of Materials and Methods, NanoCellBiology then moves through discussions of porosome discovery, calcium and SNARE-induced fusion, and vesicle swelling before winding up in a final chapter of conclusions and future studies. Succinctly packaged as SpringerBrief, this book is a must for those studying or conducting research in cell biology, biochemistry or nanobiology/nanotechnology.¡This book will be invaluable to faculty & graduate students involved in Nano Courses; Cell Biology Courses; Biophysics Courses; and Biochemistry Courses as well as practicing Cell Biologists, Biochemists and BioPhysicists. Table of contetns: Introduction --
Materials & Methods --
Porosome Discovery --
¡Calcium & SNARE-Induced Membrane Fusion --
SNAREs need to reside in opposing membrane --
Membrane curvature dictates SNARE size --
Disassembly of membrane-associated SNARE complex --
CD spectroscopy confirm membrane requirement for t-/v-SNARE assembly --
SNAREs br ing opposing bilayers closer for calcium bridging --
Membrane lipids influence SNARE complex assembly-disassembly --
Vesicle swelling and content expulsion during cell secretion --
Secretory vesicle swelling is required for intravesicular content expulsion --
Molecular mechanism of secretory vesicle swelling --
Presence of beta receptors at the secretory vesicle membrane --
Conclusion and future studies.
Título da Série: SpringerBriefs in biological imaging.
Outros Títulos: Nano cell biology of secretion
Responsabilidade: Bhanu P. Jena ; foreword by Lloyd L. Anderson.

Resumo:

Understanding live cells at the single molecule level is the most important and single major challenge facing biology and medicine today.  Ler mais...

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"This is a reference discussing the molecular mechanisms of the following problems: Exocytocis, secretion of hormones in pancreatic and excitable cells. ... This reference is of use to physiologists, Ler mais...

 
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