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NanoCellBiology of secretion : imaging its cellular and molecular underpinnings

著者: Bhanu P Jena; Lloyd L Anderson
出版商: New York : Springer, 2012.
丛书: SpringerBriefs in biological imaging.
版本/格式:   电子图书 : 文献 : 英语查看所有的版本和格式
数据库:WorldCat
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Understanding live cells at the single molecule level is the most important and single major challenge facing biology and medicine today. Opening with an explanation of Materials and Methods, this  再读一些...

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类型/形式: Electronic books
附加的形体格式: Print version:
Jena, Bhanu P.
NanoCellBiology of secretion.
New York : Springer, 2012
(DLC) 2011945438
材料类型: 文献, 互联网资源
文件类型: 互联网资源, 计算机文档
所有的著者/提供者: Bhanu P Jena; Lloyd L Anderson
ISBN: 9781461424383 1461424380
OCLC号码: 781540178
描述: 1 online resource (xii, 70 p.) : ill. (chiefly col.)
内容: Understanding live cells at the single molecule level is the most important and single major challenge facing biology and medicine today. Over the past 15 years, there has been a renewed understanding of living cells at the molecular level. Atomic Force Microscopy, Laser Force Microscopy, single secretory vesicle patch clamp studies, highresolution electron microscopy, and x-ray diffraction, are some of the tools now being used to unravel the intricacies of a living cell at the molecular level. Opening with an explanation of Materials and Methods, NanoCellBiology then moves through discussions of porosome discovery, calcium and SNARE-induced fusion, and vesicle swelling before winding up in a final chapter of conclusions and future studies. Succinctly packaged as SpringerBrief, this book is a must for those studying or conducting research in cell biology, biochemistry or nanobiology/nanotechnology. This book will be invaluable to faculty & graduate students involved in Nano Courses; Cell Biology Courses; Biophysics Courses; and Biochemistry Courses as well as practicing Cell Biologists, Biochemists and BioPhysicists. Table of contetns: Introduction.- Materials & Methods.- Porosome Discovery.- Calcium & SNARE-Induced Membrane Fusion.- SNAREs need to reside in opposing membrane.- Membrane curvature dictates SNARE size.- Disassembly of membrane-associated SNARE complex.- CD spectroscopy confirm membrane requirement for t-/v-SNARE assembly.- SNAREs bring opposing bilayers closer for calcium bridging.- Membrane lipids influence SNARE complex assembly-disassembly.- Vesicle swelling and content expulsion during cell secretion.- Secretory vesicle swelling is required for intravesicular content expulsion.- Molecular mechanism of secretory vesicle swelling.- Presence of beta receptors at the secretory vesicle membrane.- Conclusion and future studies.
丛书名: SpringerBriefs in biological imaging.
其他题名: Nano cell biology of secretion
责任: Bhanu P. Jena ; foreword by Lloyd L. Anderson.
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