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Natural product chemistry for drug discovery

Author: Antony D Buss; Mark S Butler; Royal Society of Chemistry (Great Britain)
Publisher: Cambridge : Royal Society of Chemistry, 2009.
Series: RSC biomolecular sciences, 19.
Edition/Format:   eBook : Document : EnglishView all editions and formats
Summary:
This up-to-date summary of natural product chemistry in drug discovery will appeal to scientists, professionals, postgraduates and industrial chemists.
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Genre/Form: Electronic books
Additional Physical Format: (OCoLC)465079730
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Antony D Buss; Mark S Butler; Royal Society of Chemistry (Great Britain)
ISBN: 9781847559890 1847559891 9780854041930 0854041931
OCLC Number: 642189020
Reproduction Notes: Electronic reproduction. Cambridge, England : Royal Society of Chemistry, 2010. Mode of access: World Wide Web. System requirements: Web browser. Title from title screen (viewed on June 8, 2010). Access may be restricted to users at subscribing institutions.
Description: 1 volume : illustrations ; 24 cm.
Contents: Chapter 1: Natural Products as Drugs and Leads to Drugs: the Historical Perspective; Chapter 2: Chemical Space and the Difference between Natural Products and Synthetics; Chapter 3: The Importance of Mechanism of Action Studies; Chapter 4: The Convention on Biological Diversity and its Impact on Natural Product Research; Chapter 5: Plants: Revamping the Oldest Source of Medicines with Modern Science; Chapter 6: Macromarines: a Selective Account on the Potential of Marine Sponges, Molluscs, Soft Corals and Tunicates as a Source of Therapeutically Important Molecular Structures; Chapter 7: Microorganisms: their Role in the Discovery and Development of Medicines; Chapter 8: Advances in Biological Screening for Lead Discovery; Chapter 9: Advances in Instrumentation and Automation, Dereplication and Prefractionation; Chapter 10: Natural Product Combinatorial Biosynthesis: Promises and Realities; Chapter 11: A Snapshot of Natural Product-Derived Compounds in Late Stage Clinical Development at the End of 2008; Chapter 12: From Natural Product to Clinical Trials: NPI-0052 (Salinosporamide A), a Marine Actinomycete-Derived Anticancer Agent; Chapter 13: From Natural Product to Clinical Trials: Bevirimat, a Plant-Derived Anti-AIDS Drug; Chapter 14: Daptomycin; Chapter 15: Micafungin; Chapter 16: From rapamycin to temsirolimus;
Series Title: RSC biomolecular sciences, 19.
Responsibility: edited by Antony D. Buss and Mark S. Butler.

Abstract:

This up-to-date summary of natural product chemistry in drug discovery will appeal to scientists, professionals, postgraduates and industrial chemists.  Read more...

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"This volume serves as a useful reminder that even as the first decade of the 21st century comes to a close, natural products are still a valuable resource for the new therapeutic agents and new drug Read more...

 
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