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Neurodegeneration : methods and protocols

Author: Giovanni Manfredi; Hibiki Kawamata
Publisher: New York : Humana Press, ©2011.
Series: Methods in molecular biology (Clifton, N.J.), v. 793.; Springer protocols (Series)
Edition/Format:   eBook : Document : EnglishView all editions and formats
Summary:
Neurodegenerative disorders, such as Alzheimer's and Parkinson's disease are a growing burden on our society. Understanding and treating these common diseases is one of the major current challenges for the biomedical field. In Neurodegeneration: Methods and Protocols, experts in the field tackle this challenge and present cutting-edge analytical and technological approaches to study the mechanisms underlying  Read more...
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Genre/Form: Laboratory manuals
Electronic books
Additional Physical Format: Print version:
Neurodegeneration.
New York : Humana Press, ©2011
(DLC) 2011935542
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Giovanni Manfredi; Hibiki Kawamata
ISBN: 9781617793288 1617793280 1617793272 9781617793271
OCLC Number: 757339182
Language Note: English.
Description: 1 online resource (xv, 512 pages).
Contents: Introduction to neurodegenerative diseases and related techniques --
In vivo and in vitro determination of cell death markers in neurons --
Degenerating processes identified by electron microscopic immunocytochemical methods --
Isolation and culture of neurons and astrocytes from the mouse brain cortex --
Isolation and culture of postnatal spinal motoneurons --
Converting human pluripotent stem cells to neural tissue and neurons to model neurodegeneration --
Neural differentiation of induced pluripotent stem cells --
Developing yeast models of human neurodegenerative disorders --
Modeling dopamine neuron degeneration in Caenorhabditis elegans --
Role of the proteasome in fly models of neurodegeneration --
Modeling neurodegenerative diseases in zebrafish embryos --
Practical considerations of genetic rodent models for neurodegenerative diseases --
Modeling focal cerebral ischemia in vivo --
Pharmacological models of Parkinson's disease in rodents.
Series Title: Methods in molecular biology (Clifton, N.J.), v. 793.; Springer protocols (Series)
Responsibility: edited by Giovanni Manfredi, Hibiki Kawamata.

Abstract:

Neurodegeneration tackles the challenges involved with neurodegenerative disorders, such as Alzheimer's and Parkinson's disease. The text presents cutting-edge analytical and technological approaches  Read more...

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From the reviews:"The authors describe various cell and molecular systems related to neurodegeneration research. ... there are a lot of protocols and methods described by the book that can be used by Read more...

 
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