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Neuroprotective signal transduction

Author: Mark Paul Mattson
Publisher: Totowa, N.J. : Humana Press, ©1998.
Series: Contemporary neuroscience.
Edition/Format:   eBook : Document : EnglishView all editions and formats
Database:WorldCat
Summary:
In Neuroprotective Signal Transduction prominent researchers and clinicians focus on how inter- and intracellular signaling mechanisms prevent the degeneration and death of neurons occurring in both acute and chronic neurodegenerative disorders. Authoritative contributions dissect the signaling pathways of an array of neuroprotective factors-ranging from neurotrophins (NGF, BDNF, NT-3, and NT-4/5), to growth factors  Read more...
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Genre/Form: Electronic books
Additional Physical Format: Print version:
Neuroprotective signal transduction.
Totowa, N.J. : Humana Press, ©1998
(DLC) 97037497
(OCoLC)37553767
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Mark Paul Mattson
ISBN: 9781592594757 1592594751 9781475759686 1475759681
OCLC Number: 667019277
Reproduction Notes: Electronic reproduction. [S.l.] : HathiTrust Digital Library, 2010. MiAaHDL
Description: 1 online resource (x, 347 pages) : illustrations.
Details: Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002.
Contents: Neuroprotective Strategies Involving the Neurotrophins and Their Signaling Pathways --
Nerve Growth Factor and Its Receptors in the Primate Forebrain --
Molecular Mechanisms of Neuroprotection from Neuronal Death by Trophic Factor Deprivation --
Gene Induction and Neuronal Apoptosis --
Clinical Potential of Compounds That Stimulate Nerve Growth Factor Production --
Preclinical Trials of Basic Fibroblast Growth Factor (bFGF) in Animal Models of Stroke --
Transforming Growth Factor-? Signaling and Neuroprotection --
Protective and Regenerative Properties of GDNF in the Central Nervous System --
Tumor Necrosis Factor --
Neuroprotective Strategies Based on Interleukin Signaling --
Signaling by?-Amyloid Precursor Protein --
Clinical Potential of Agents That Affect Thrombin Signaling in Degenerative and Traumatic Neurologic Disorders --
Thrombin and Thrombin Inhibitors --
Deleterious and Salutary Effects of Steroid Hormones in the Nervous System --
Therapeutic Potential of Leukocyte Antiadhesion Strategies in CNS Ischemia --
Neuroprotective Strategies Based on Targeting of Postreceptor Signaling Events.
Series Title: Contemporary neuroscience.
Responsibility: edited by Mark P. Mattson.

Abstract:

This collection of reviews illuminates multiple aspects of the signal transduction cascades involved in neuronal injury and protection. It should help neurologists working in both clinical and basic  Read more...

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Primary Entity

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