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Neutralization of croatalidae venom induced platelet aggregation by affinity chromatography isolated IgG to Crotalus viridis helleri venom.
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Neutralization of croatalidae venom induced platelet aggregation by affinity chromatography isolated IgG to Crotalus viridis helleri venom.

Author: D Bar-Or; Sullivan JB Jr; E Black; FE Russell
Edition/Format: Article Article : English
Publication:Journal of toxicology. Clinical toxicology, 1984 Jul; 22(1): 1-9
Database:From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.
Summary:
IgG was isolated from commercial antivenin by affinity chromatography using Crotalus viridis helleri venom as an affinant. This purified IgG was demonstrated to be more effective than the commercial antivenin in preventing platelet aggregation induced by four separate crotalid venoms in vitro. Affinity chromatography appears to be an effective means for specific, polyvalent IgG isolation and purification.
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Details

Document Type: Article
All Authors / Contributors: D Bar-Or; Sullivan JB Jr; E Black; FE Russell
ISSN:0731-3810
OCLC Number: 114755533
Language Note: English
Awards:

Abstract:

IgG was isolated from commercial antivenin by affinity chromatography using Crotalus viridis helleri venom as an affinant. This purified IgG was demonstrated to be more effective than the commercial antivenin in preventing platelet aggregation induced by four separate crotalid venoms in vitro. Affinity chromatography appears to be an effective means for specific, polyvalent IgG isolation and purification.

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