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The neutrophil

Author: Jon S Abramson; J Gary Wheeler
Publisher: Oxford ; New York : IRL Press at Oxford University Press, ©1993.
Series: Natural immune system.
Edition/Format:   Print book : EnglishView all editions and formats
Database:WorldCat
Summary:
Historically, the study of immunology has focused to a large extent on the central role of antigen recognition and antibody structure and function in the response of the host to infection. In the last two decades, however, scientists have been turning their attention to the involvement of various cell types in host defence. Cells such as the macrophage, the natural killer cell, the neutrophil, and other humoral
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Additional Physical Format: Online version:
Neutrophil.
Oxford ; New York : IRL Press at Oxford University Press, ©1993
(OCoLC)610112006
Material Type: Internet resource
Document Type: Book, Internet Resource
All Authors / Contributors: Jon S Abramson; J Gary Wheeler
ISBN: 0199633746 9780199633746 0199633738 9780199633739
OCLC Number: 27036917
Description: xxv, 306 pages : illustrations ; 24 cm.
Contents: Neonatal neutrophil maturation, kinetics, and function / V.S. Kanwar and M.S. Cairo --
Neutrophil receptors and modulation of the immune response / C. Rosales and E.J. Brown --
Signal transduction in neutrophil oxidative metabolism and chemotaxis / L.C. McPhail and L. Harvath --
Neutrophil phagocytosis and killing: normal function and microbial evasion / J. Verhoef and M.R. Visser --
Microbial and pharmacological induction of neutrophil dysfunction / J.G. Wheeler and J.S. Abramson --
Congenital neutrophil deficiencies / E.L. Mills and F.J.D. Noya --
Neutrophil-mediated tissue injury / J.A. Leff and J.E. Repine --
Therapeutic modulation of neutrophil number and function / L.A. Boxer and R.F. Todd III.
Series Title: Natural immune system.
Responsibility: edited by Jon S. Abramson and J. Gary Wheeler.

Abstract:

Historically, the study of immunology has focused to a large extent on the central role of antigen recognition and antibody structure and function in the response of the host to infection. In the last two decades, however, scientists have been turning their attention to the involvement of various cell types in host defence. Cells such as the macrophage, the natural killer cell, the neutrophil, and other humoral factors comprise this innate or 'natural' immune system.

They can take part in various immune responses without prior sensitization, and have important modulatory effects on later, specific responses.

This volume provides a collection of reviews written by leading scientists, covering a variety of topics relating to the biology and function of the neutrophil, and its role in disease. A broad range of chapters includes discussions of the neutrophil's basic cell biology and normal function, followed by specific examples of diseases resulting from neutrophil dysfunction and deficiency. The concepts in each chapter are brought to life through the use of clinical case studies.

Advanced students and researchers in immunology, cell biology, and medicine will find The Neutrophil to be a valuable source of current research into this exciting field.

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