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New drugs for asthma, allergy, and COPD

Author: T T Hansel; Peter J Barnes
Publisher: Basel ; New York : Karger, ©2001.
Series: Progress in respiratory research, v. 31.
Edition/Format:   eBook : Document : EnglishView all editions and formats
Summary:

This book provides a state-of-the-art account by academic respiratory physicians and senior pharmaceutical industry personnel on the development of new drugs for asthma, allergy and COPD. Never  Read more...

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Genre/Form: Electronic books
Additional Physical Format: Print version:
New drugs for asthma, allergy, and COPD.
Basel ; New York : Karger, ©2001
(DLC) 00050644
(OCoLC)45167223
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: T T Hansel; Peter J Barnes
ISBN: 0585441529 9780585441528 3805568622 9783805568623 9783318004243 3318004243
OCLC Number: 52124147
Description: 1 online resource (x, 389 pages) : illustrations (some color).
Contents: ""Contents""; ""Foreword""; ""Preface""; ""General Aspects""; ""The Need for New Therapy""; ""Current Therapy for Asthma""; ""Current Therapy for COPD""; ""Pharmacogenetics""; ""Delivery of Biologics to the Lung""; ""Immunopathology: Comparison of COPD and Asthma""; ""Monitoring Lung Function""; ""Airway Hyperresponsiveness""; ""Airways Remodelling""; ""Exhaled Breath Analysis""; ""Clinical Studies on New Drugs""; ""Bronchodilators""; ""Bronchodilators: An Overview""; ""Long-Acting ß""; ""Agonists""; ""Single-Isomer ß-Agonists""; ""Anticholinergics: Tiotropium"" ""Potassium Channel Openers""""Urodilatin""; ""Steroids""; ""Steroids: An Overview""; ""Ciclesonide: An On-Site-Activated Steroid""; ""Soft Steroids""; ""Dissociated Steroids""; ""Oestradiol Metabolites""; ""Leukotriene Inhibitors""; ""Leukotriene Inhibitors: An Overview""; ""Cysteinyl Leukotriene Antagonists""; ""5-Lipoxygenase Inhibitors""; ""LTB4 Antagonism""; ""Mediator Inhibitors and Agonists""; ""H1-Antihistamines""; ""Histamine H3 Antagonists""; ""Kinin Receptor Antagonists""; ""Endothelin Antagonists""; ""Tachykinin Antagonists""; ""Antioxidants""; ""Selective iNOS Inhibitors"" ""Mucus Regulation""""P2Y Receptor Agonists""; ""Protease Inhibitors""; ""Tryptase Inhibition""; ""Neutrophil Elastase Inhibitors""; ""Macrophage Metalloelastase Inhibitors""; ""Allergen- and IgE-Directed Therapies""; ""Allergen, IgE and Mast-Cell-Directed Therapies: An Overview""; ""Allergen Immunotherapy""; ""Peptide Immunotherapy""; ""Recombinant Allergens""; ""Anti-IgE Antibody""; ""CD23""; ""T Cell Immunomodulation""; ""T Cell Immunomodulation: An Overview""; ""Costimulatory Molecules in T Cell Activation""; ""GATA-3: A Th2-Selective Target""; ""Mycobacterial Immunization"" ""CpG Oligodeoxynucleotides""""CD8 T Cells: Potential Therapeutic Targets?""; ""Macrocyclic Immunosuppressants""; ""Cytokine-Directed Therapy""; ""Cytokines: An Overview""; ""TNF Antagonism""; ""GM-CSF Antagonists""; ""Interleukin-4 Antagonism""; ""Interleukin- 13 Antagonism""; ""Interleukin-5 Antagonism""; ""Interleukin- 10""; ""Interleukin- 12, Interleukin- 18 and Interferon- �""; ""Chemokine Receptor Inhibition""; ""Chemokines: An Overview""; ""Chemokine Receptors on Th1 and Th2 Cells""; ""CCR-3 Antagonists""; ""Interleukin-8 Receptor (CXCR2) Antagonists"" ""Adhesion Molecule Inhibitors""""Adhesion Molecule Antagonism: An Overview""; ""Small-Molecule VLA-4 Antagonists""; ""Selectin Antagonists""; ""ICAM- 1 and VCAM- 1 Antagonists""; ""Inhibition of Cell Signalling""; ""Eosinophil G-Protein-Coupled Receptor Signalling: An Overview""; ""Phosphodiesterase 4 Inhibitors""; ""Therapies Acting on Transcription""; ""Therapies Acting on Transcription: An Overview""; ""Chromatin Modification""; ""Activator Protein- 1 and Nuclear Factor- Kappa B""; ""Inhibition of p38 MAP Kinase""; ""STAT6""; ""Retinoids""; ""Genetic Therapy""
Series Title: Progress in respiratory research, v. 31.
Responsibility: volume editors, Trevor T. Hansel, Peter J. Barnes.

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