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New strategies in stroke intervention : ionic transporters, pumps, and new channels

Author: Lucio Annunziato
Publisher: New York : Humana Press, ©2009.
Series: Contemporary neuroscience.
Edition/Format:   Print book : EnglishView all editions and formats
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This book on stroke intervention is a groundbreaking review of ionic channels, pumps, and transporters as regulators of neuronal ionic homeostasis, providing a better understanding of ischemic brain  Read more...

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Document Type: Book
All Authors / Contributors: Lucio Annunziato
ISBN: 9781607612797 1607612798 9781607612803 1607612801
OCLC Number: 401157174
Description: xv, 254 pages : illustrations.
Contents: Table of Contents:PrefaceChapter 1. Basis of Ionic Dysregulation in Cerebral IschemiaThiruma V. Arumugam, Eitan Okun, and Mark P. Mattson Chapter 2. Why have ionotropic and metabotropic glutamate antagonists failed in stroke therapy? Gianfranco Di Renzo, Giuseppe Pignataro, Lucio Annunziato Chapter 3. Mitochondrial channels as potential target for a pharmacological strategies in brain ischemia. Rosemary H. Milton and Michael R. DuchenChapter 4. Endoplasmic Reticulum Calcium Homeostasis and Neuronal Pathophysiology of Stroke Alexei VerkhratskyChapter 5. The Na(+)/Ca(2+) Exchanger: a target for therapeutic intervention in cerebral ischemiaLucio Annunziato, Pasquale Molinaro, Agnese Secondo, Anna Pannaccione, Antonella Scorziello, Giuseppe Pignataro, Ornella Cuomo, Rossana Strabella, Francesca Boscia, Alessandra Spinali, Gianfranco Di RenzoChapter 6. The 'loop' Diuretic Drug Bumetanide-sensitive Na+-K+-Cl - Cotransporter in Cerebral IschemiaDandan SunChapter 7. The Na(+)/H(+) exchanger: a target for therapeutic intervention in cerebral ischemiaJin Xue and Gabriel G. HaddadChapter 8. The Na+/K+-ATPase as a drug target for ischemic strokeMelissa A. Gottron and Donald C. LoChapter 9. Acid-Sensing Ion Channels (ASICs): New Targets in Stroke TreatmentGiuseppe PignataroChapter 10. Role of TRPM7 in Ischemic CNS InjuryMichael F. Jackson, Hong-Shuo Sun, Michael Tymianski, and John F. MacDonaldChapter 11. Subtypes of voltage-gated Ca2+ channels and ischemic brain injurySoon-Tae Lee, Daejong Jeon, and Kon ChuChapter 12. The diverse roles of K+ channels in brain ischemiaHiroaki Misonou and James S. TrimmerChapter 13. Clinical Trials with Drugs Targeting Ionic Channels, Antiporters, and Pumps in Ischemic StrokeAlessandra Spinali, Giuseppe Pignataro, Gianfranco Di Renzo, Lucio Annunziato
Series Title: Contemporary neuroscience.
Responsibility: Lucio Annunziato, editor.

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From the reviews:"This book on ionic channels in cerebral ischemia is a very detailed analysis of the recent literature on the subject with a wide and in depth scope. The book is meant for the Read more...

 
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