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New targets in inflammation : inhibitors of COX-2 or adhesion molecules : proceedings of a conference held on April 15-16, 1996, in New Orleans, USA, supported by an educational grant from Boehringer Ingelheim

Author: Nicolás G Bazán; Jack H Botting; John R Vane
Publisher: Dordrecht ; Boston : Kluwer Academic Publishers : William Harvey Press, ©1996.
Edition/Format:   Print book : Conference publication : EnglishView all editions and formats
Summary:

This volume of conference proceedings reviews the general pathophysiological significance of the isoforms of cyclooxygenase, and the likely value of selective COX-2 inhibitors in the treatment of  Read more...

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Genre/Form: Congresses
Conference papers and proceedings
Additional Physical Format: Online version:
New targets in inflammation.
Dordrecht ; Boston : Kluwer Academic Publishers : William Harvey Press, ©1996
(OCoLC)606121959
Online version:
New targets in inflammation.
Dordrecht ; Boston : Kluwer Academic Publishers : William Harvey Press, ©1996
(OCoLC)607125134
Material Type: Conference publication
Document Type: Book
All Authors / Contributors: Nicolás G Bazán; Jack H Botting; John R Vane
ISBN: 0792387147 9780792387145
OCLC Number: 36842482
Description: 147 pages : illustrations ; 25 cm
Contents: The history of anti-inflammatory drugs and their mechanism of action / J.R. Vane --
Structure of prostaglandin H2 synthase-1 (COX-1) and its NSAID binding sites / P.J. Loll --
Differential inhibition of cyclooxygenases 1 and 2 by NSAIDs / M. Pairet --
Blockade of inflammatory hyperalgesia and cyclooxygenase-2 / S.H. Ferreira --
Brain COX-2 in experimental models of epilepsy and stroke: signalling pathways leading to enhanced expression / N.G. Bazan --
New highly selective cyclooxygenase-2 inhibitors / A.W. Ford-Hutchinson --
Characteristics of cyclooxygenase-1 and cyclooxygenase-2-deficient mice / S.G. Morham --
X-raycrystal structure of human cyclooxygenase-2 / M. Browner --
Risk of gastrointestinal side effects caused by non-steroid anti-inflammatory drugs (NSAIDs) / H. Jick --
Expression and regulation of cyclooxygenase-2 in synovial tissues of arthritic patients / L.J. Crofford --
Differential target tissue presentation and COX-1/COX-2 inhibitors by non-steroid anti-inflammatory drugs: a rationale for a new classification / H. Fenner --
Clinical experience with meloxicam, a selective COX-2 inhibitor / W. Bolten --
Enzymatic regulation of the prostaglandin response in a human model of inflammation / B.F. Adam --
Cyclooxygenase-2 and intestinal cancer / R.N. DuBois --
Cytokines and adhesion molecules in the lung inflammatory response / P.A. Ward --
Adhesion molecules as targets for therapy in rheumatoid arthritis / P.E. Lipsky.
Responsibility: edited by Nicolas Bazan, Jack Botting, and Sir John Vane.

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Primary Entity

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