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New Therapeutic Targets in Rheumatoid Arthritis

Author: Michael J Parnham; Paul-Peter Tak
Publisher: Basel : Birkhäuser Basel, 2009.
Series: PIR (Series)
Edition/Format:   eBook : Document : EnglishView all editions and formats
Summary:
Focuses on therapeutic targets that were identified after TNF blockade. This book discusses the biological rationale in detail, including in vitro work and work in animal models, and where appropriate, results form clinical trials. It is of interest to rheumatologists, immunologists, internists, and investigators in immunology and rheumatology.
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Genre/Form: Electronic books
Aufsatzsammlung
Additional Physical Format: Print version:
New therapeutic targets in rheumatoid arthritis.
Basel ; Boston : Birkhäuser, ©2009
(DLC) 2009921933
(OCoLC)319207636
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Michael J Parnham; Paul-Peter Tak
ISBN: 9783764382384 3764382384
OCLC Number: 428883042
Description: 1 online resource (: v.: digital.
Contents: B cell targets in rheumatoid arthritis; Co-stimulatory pathways in the therapy of rheumatoid arthritis; Immunobiology of IL-6 --
Tocilizumab (humanised anti-IL-6 receptor antibody) for the treatment of rheumatoid arthritis; Role of IL-1 in erosive arthritis, lessons from animal models; Interleukin-15; IL-17 and Th17 cells, key players in arthritis; Role of IL-18 in inflammatory diseases; Chemokines and chemokine receptors; Signaling pathways in rheumatoid arthritis; Targeting oncostatin M in the treatment of rheumatoid arthritis; Targeting the epigenetic modifications of synovial cells.
Series Title: PIR (Series)
Responsibility: edited by Michael J. Parnham, Paul-Peter Tak.

Abstract:

This volume focuses on therapeutic targets that were identified after TNF blockade. All these targets have recently been registered or are currently under development for the treatment of rheumatoid  Read more...

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